evidencegaps
Primary study · included by 1 review

Significance of immunohistochemical overexpression of cyclooxygenase-2 in overall and disease-free survival of oral squamous cell carcinoma patients.

Ali 2018 · Adnan Ali S M, Naeem S, Mirza Y, et al. · The Journal of laryngology and otology · 2018

Included by

Cyclooxygenase-2 (COX-2) as a Potential Prognostic Marker in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
Non-Cochrane · prognostic · 2026 · cited as Ali 2018 · Figure 2
Outcome this study informsPooled effectEvidenceCertainty
Progression-free survival
High COX-2 expression (immunohistochemistry) vs Low COX-2 expression
HR 1.86 [1.21, 2.87]3 studiesGRADE not reported
Overall survival
High COX-2 expression (immunohistochemistry) vs Low COX-2 expression
HR 1.49 [1.06, 2.1]8 studiesGRADE not reported

1 including review in total.