Primary study · included by 1 review

Is Low-level laser therapy and gaseous ozone application effective on osseointegration of immediately loaded implants?

Karaca 2018 · Karaca I R, Ergun G, Ozturk D N · Nigerian journal of clinical practice · 2018

Included by

Photobiomodulation in Dental Implant Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Non-Cochrane · intervention · 2026 · cited as Karaca 2018 · Reference 30; Figure 2
Outcome this study informsPooled effectEvidenceCertainty
Implant stability (ISQ): association of energy dose with effect
Adjunctive photobiomodulation vs Sham or no photobiomodulation · 12 weeks
meta-regression coefficient -0.076 [-0.295, 0.143]6 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 3 weeks
MD 1.95 [-0.31, 4.21]4 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · baseline
MD 0.02 [-0.96, 1]12 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · baseline
MD -0.14 [-0.54, 0.26]3 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 7 days
MD -0.1 [-0.37, 0.16]3 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · all time points
MD -0.27 [-0.35, -0.19]6 studiesModerate
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 2 weeks
MD 1.85 [-0.68, 4.38]2 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 9 weeks
MD 1.56 [-4.49, 7.62]2 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 5 days
MD -0.29 [-0.38, -0.2]3 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 6 weeks
MD 2.95 [-0.15, 6.06]5 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 2 days
MD -0.31 [-1.2, 0.57]3 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 3 days
MD -0.25 [-0.56, 0.05]5 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · all time points
MD 1.26 [0.61, 1.91]13 studiesLow
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 6 months
MD 1.65 [-0.53, 3.83]3 studiesGRADE not reported
Postoperative pain (VAS/NRS)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 1 day
MD -0.35 [-0.66, -0.03]6 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 7 days
MD 1.43 [-1, 3.86]2 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 10 days
MD 2.27 [0.4, 4.13]3 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 4 weeks
MD 1.51 [-0.99, 4.02]3 studiesGRADE not reported
Implant stability (ISQ)
Adjunctive photobiomodulation (laser or LED) vs Sham or no photobiomodulation · 12 weeks
MD 0.89 [-0.78, 2.55]6 studiesGRADE not reported

1 including review in total.