Primary study · included by 1 review
MicroRNA-146a and microRNA-155 as novel crevicular fluid biomarkers for periodontitis in non-diabetic and type 2 diabetic patients.
Radovic 2018 · Radović Nikola, Nikolić Jakoba Nataša, Petrović Nina, et al. · Journal of clinical periodontology · 2018
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.814 | 4 studies | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.658 | 2 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.85 | 2 studies | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.727 | 2 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.85 [0.77, 0.91] | 5 studies | Moderate |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.841 | 4 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.84 | 5 studies | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 1.000 | 2 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.83 | 3 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.860 | 4 studies | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.86 | 3 studies | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.84 [0.60, 0.93] | 3 studies | Low |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.829 | 4 studies | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.87 | 1 study | GRADE not reported |
Pooled sensitivity miR-146 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.85 | 2 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.850 | 4 studies | GRADE not reported |
1 including review in total.