Primary study · included by 1 review

Alterations in oral bacterial communities are associated with risk factors for oral and oropharyngeal cancer.

Bornigen 2017 · Börnigen Daniela, Ren Boyu, Pickard Robert, et al. · Scientific reports · 2017

Included by

Risk of cancer in periodontal disease: an umbrella review of meta-analyses.

Non-Cochrane · aetiology · 2026 · cited as Bornigen 2017 · Results, Overlap assessment (primary studies added in the author's own meta-analysis; references 32-34, 39-47)

Outcome this study informs	Pooled effect	Evidence	Certainty
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.20 [1.19, 4.06]	5 studies · 3257 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 3.19 [2.09, 4.85]	7 studies · 2464 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 4.31 [1.56, 11.90]	2 studies · 951 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	RR 1.07 [0.94, 1.23]	5 studies · 1069853 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	RR 1.13 [0.80, 1.60]	2 studies · 114244 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.23 [0.58, 8.61]	2 studies · 62304 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) · Long follow-up	RR 0.97 [0.86, 1.11]	3 studies · 961746 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.46 [1.62, 3.74]	8 studies · 71622 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.67 [1.67, 4.27]	2 studies · 2172 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 4.68 [0.75, 29.33]	2 studies · 4018 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 3.17 [1.78, 5.64]	9 studies · 82844 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.45 [1.52, 3.94]	7 studies · 57688 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.29 [1.11, 4.76]	4 studies · 63741 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure) · Short follow-up	RR 1.20 [1.09, 1.32]	2 studies · 108107 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	RR 1.05 [0.88, 1.26]	3 studies · 955609 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.11 [0.74, 5.98]	3 studies · 48902 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 1.31 [1.10, 1.56]	3 studies · 2306 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.83 [1.83, 4.38]	7 studies · 71722 participants	GRADE not reported
Risk of head and neck cancer Periodontal diseases (gingivitis or periodontitis, as defined in each meta-analysis) vs No periodontal disease (absence of exposure)	OR 2.42 [1.85, 3.17]	18 studies · 156693 participants	GRADE not reported

1 including review in total.