Primary study · included by 1 review

Human oral microbiome and prospective risk for pancreatic cancer: a population-based nested case-control study.

Fan 2018 · Fan Xiaozhou, Alekseyenko Alexander V, Wu Jing, et al. · Gut · 2018

Included by

Periodontitis and Pancreatic Cancer Risk: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis.

Non-Cochrane · aetiology · 2026 · cited as Fan 2018 · Table 1; Figure 3; reference list

Outcome this study informs	Pooled effect	Evidence	Certainty
Pancreatic cancer incidence or risk Periodontitis (clinical, radiographic, self-reported, registry diagnosis or tooth loss attributable to periodontal disease) vs No periodontitis or healthy/mild periodontal status	logHR 0.44 [-0.18, 1.06]	2 studies	GRADE not reported
Pancreatic cancer incidence or risk Periodontitis (clinical, radiographic, self-reported, registry diagnosis or tooth loss attributable to periodontal disease) vs No periodontitis or healthy/mild periodontal status	HR 1.56 [1.28, 1.89]	8 studies · 476245 participants	Very low
Pancreatic cancer incidence or risk Periodontitis (clinical, radiographic, self-reported, registry diagnosis or tooth loss attributable to periodontal disease) vs No periodontitis or healthy/mild periodontal status	logHR 0.45 [0.20, 0.71]	2 studies	GRADE not reported
Pancreatic cancer incidence or risk Periodontitis (clinical, radiographic, self-reported, registry diagnosis or tooth loss attributable to periodontal disease) vs No periodontitis or healthy/mild periodontal status	logHR 0.53 [0.29, 0.76]	4 studies	GRADE not reported

1 including review in total.