evidencegaps
Primary study · included by 1 review

Statins and IL-1β, IL-10, and MPO Levels in Gingival Crevicular Fluid: Preliminary Results.

Ari 2016 · Cicek Ari Vuslat, Ilarslan Yagmur Deniz, Erman Baran, et al. · Inflammation · 2016

Included by

Effect of renin-angiotensin-aldosterone system inhibitor and statin medication on periodontal status of patients at risk of cardiovascular disease: a systematic review and meta-analysis.
Non-Cochrane · intervention · 2026 · cited as Ari VC 2016 · Table 1; reference list; Figs. 3-5
Outcome this study informsPooled effectEvidenceCertainty
Probing depth (mm)
Systemic statin medication vs Non-statin groups (diet or normolipidemic controls) · Not specified
MD -0.38 [-0.53, -0.23]4 studies · 232 participantsGRADE not reported
Bleeding on probing index (%)
Systemic statin medication vs Non-statin groups (diet or normolipidemic controls) · Not specified
MD -13.52 [-23.20, -3.83]3 studies · 175 participantsGRADE not reported
Clinical attachment loss (mm)
Systemic statin medication vs Non-statin groups (diet or normolipidemic controls) · Not specified
MD -0.16 [-0.40, 0.07]4 studies · 232 participantsGRADE not reported
Bleeding on probing (BOP) index, %
Systemic statin medication (simvastatin, lovastatin or unspecified statin) vs Non-statin comparison (diet-controlled or normolipidemic participants) · Not specified
MD -13.52 [-23.20, -3.83]3 studies · 175 participantsGRADE not reported

1 including review in total.