Primary study · included by 1 review

Periodontal disease and risk of all cancers among male never smokers: an updated analysis of the Health Professionals Follow-up Study.

Michaud DS (1) 2016 · Michaud D S, Kelsey K T, Papathanasiou E, et al. · Annals of oncology : official journal of the European Society for Medical Oncology · 2016

Included by

Associations of oral health with colorectal cancer risk: accumulated evidences from observational studies.

Non-Cochrane · aetiology · 2026 · cited as Michaud (1) 2016 · Table 1; References 11, 18-31

Outcome this study informs	Pooled effect	Evidence	Certainty
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.08 [0.97, 1.21]	8 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.22 [1.03, 1.44]	7 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.17 [1.02, 1.33]	3 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.25 [1.04, 1.50]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.22 [1.01, 1.47]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.39 [1.01, 1.90]	3 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.16 [0.94, 1.42]	3 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.26 [1.02, 1.57]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.12 [0.91, 1.38]	5 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.22 [1.01, 1.47]	10 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.08 [0.97, 1.20]	8 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.09 [1.00, 1.18]	8 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.13 [1.10, 1.16]	8 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.01 [0.87, 1.18]	8 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.22 [1.02, 1.47]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 0.99 [0.74, 1.33]	2 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.08 [0.98, 1.19]	6 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.07 [0.91, 1.25]	7 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 0.88 [0.71, 1.08]	3 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 0.96 [0.84, 1.09]	4 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.08 [0.96, 1.20]	8 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.24 [1.04, 1.48]	11 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.64 [1.50, 1.79]	2 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.09 [0.99, 1.21]	8 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.21 [1.00, 1.45]	10 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 0.98 [0.83, 1.15]	6 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.01 [0.85, 1.21]	8 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.07 [0.96, 1.20]	8 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.14 [1.01, 1.29]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.29 [1.08, 1.55]	10 studies	GRADE not reported
Colorectal cancer risk Tooth loss vs No or less tooth loss	HR 1.09 [0.98, 1.21]	6 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.28 [1.06, 1.55]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.22 [0.84, 1.79]	4 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.62 [1.49, 1.76]	5 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.23 [1.03, 1.47]	10 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.14 [1.04, 1.25]	4 studies	GRADE not reported
Colorectal cancer risk Periodontitis vs No periodontitis	HR 1.26 [1.05, 1.53]	10 studies	GRADE not reported

1 including review in total.