Primary study · included by 1 review
Cyclooxygenase-2 expression is associated with vascular endothelial growth factor-c and lymph node metastasis in human oral tongue cancer.
Morita 2014 · Morita Yoshihiro, Morita Nobuo, Hata Kenji, et al. · Oral surgery, oral medicine, oral pathology and oral radiology · 2014
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Advanced TNM stage (III/IV) High COX-2 expression (immunohistochemistry) vs Low COX-2 expression | OR 2.68 [1.43, 5.02] | 3 studies · 203 participants | GRADE not reported |
Advanced T stage (T3/T4) High COX-2 expression (immunohistochemistry) vs Low COX-2 expression | OR 2.91 [1.52, 5.55] | 3 studies · 203 participants | GRADE not reported |
Lymph node metastasis High COX-2 expression (immunohistochemistry) vs Low COX-2 expression | OR 2.16 [0.71, 6.57] | 3 studies · 203 participants | GRADE not reported |
Overall survival High COX-2 expression (immunohistochemistry) vs Low COX-2 expression | HR 1.49 [1.06, 2.1] | 8 studies | GRADE not reported |
1 including review in total.