evidencegaps
Primary study · included by 1 review

Cancer risk among gingivitis and periodontitis patients: a nationwide cohort study.

Wen 2014 · Wen B-W, Tsai C-S, Lin C-L, et al. · QJM : monthly journal of the Association of Physicians · 2014

Included by

Periodontitis and Oral and Oropharyngeal Cancer Risk: A Systematic Review and Meta-Analysis with Exploratory Evidence on Tumor-Associated Porphyromonas gingivalis.
Non-Cochrane · aetiology · 2026 · cited as Wen 2014 · Table 1; Table 2; Reference list
Outcome this study informsPooled effectEvidenceCertainty
Risk, incidence or mortality of oral and/or oropharyngeal cancer
Clinically defined periodontitis (exposure) vs No periodontitis or periodontally healthy
Pooled risk estimates ranged approximately from RR about 1.9 to 2.6 after sequential exclusion of each study, remaining above unity5 studiesGRADE not reported
Risk, incidence or mortality of oral and/or oropharyngeal cancer
Clinically defined periodontitis (exposure) vs No periodontitis or periodontally healthy
HR 2.14 [1.53, 2.98]6 studiesGRADE not reported

1 including review in total.