Primary study · included by 1 review

Salivary enzymes as diagnostic markers for detection of gingival/periodontal disease and their correlation with the severity of the disease.

Dabra 2012 · Dabra Sarita, China Kamalpreet, Kaushik Alka · Journal of Indian Society of Periodontology · 2012

Included by

Association between salivary alkaline phosphatase levels and periodontal disease: a systematic review and meta-analysis.

Non-Cochrane · aetiology · 2026 · cited as Dabra 2012 · Table 1; ref 30; Fig. 2A

Outcome this study informs	Pooled effect	Evidence	Certainty
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 41 [18.07, 63.92]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 43.76 [19.31, 68.21]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 37.67 [20.93, 54.41]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 49.94 [24.44, 75.45]	10 studies · 683 participants	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 46.31 [22.03, 70.58]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 27.39 [13.21, 41.58]	6 studies · 444 participants	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 52.55 [0.82, 104.28]	4 studies · 259 participants	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 47.75 [24.45, 71.06]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 44.44 [19.86, 69.01]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Gingivitis vs Periodontally healthy · Baseline	MD 16.05 [-10.14, 42.25]	4 studies · 238 participants	Very low
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 46.01 [21.62, 70.4]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Gingivitis · Baseline	MD 38.94 [-32.36, 110.25]	4 studies · 220 participants	Very low
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 19.43 [-139.17, 178.03]	2 studies · 144 participants	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 41.7 [18.5, 64.9]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 63.65 [19.74, 107.57]	6 studies · 383 participants	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 46.98 [23.09, 70.86]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 48.07 [25.14, 71]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 45.98 [21.58, 70.39]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 46.22 [21.89, 70.54]	11 studies	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 40.88 [9.53, 72.22]	8 studies · 568 participants	GRADE not reported
Salivary alkaline phosphatase activity (U/L or IU/L) Periodontitis vs Periodontally healthy · Baseline	MD 44.62 [22.54, 66.69]	12 studies · 817 participants	Very low

1 including review in total.