evidencegaps
Primary study · included by 1 review

Saliva concentrations of RANKL and osteoprotegerin in smoker versus non-smoker chronic periodontitis patients.

Buduneli 2008 · Buduneli Nurcan, Biyikoğlu Başak, Sherrabeh Sakhr, et al. · Journal of clinical periodontology · 2008

Included by

A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysis.
Non-Cochrane · aetiology · 2025 · cited as Buduneli 2008 · Table 1; Figures 2-11; References
Outcome this study informsPooled effectEvidenceCertainty
Receptor activator of nuclear factor kappa-B ligand (RANKL) level in gingival crevicular fluid
Smoking (smoker chronic periodontitis patients) vs Non-smoker chronic periodontitis patients
MD 1.49 [0.85, 2.14]4 studies · 176 participantsGRADE not reported
Osteoprotegerin (OPG) level in gingival crevicular fluid
Smoking (smoker chronic periodontitis patients) vs Non-smoker chronic periodontitis patients
MD -1.52 [-2.98, -0.06]4 studies · 176 participantsGRADE not reported

1 including review in total.