Primary study · included by 3 reviews

A comparison of treatment impacts between Invisalign aligner and fixed appliance therapy during the first week of treatment.

Miller 2007 · Miller Kevin B, McGorray Susan P, Womack Randy, et al. · American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2007

Included by

Outcome this study informsPooled effectEvidenceCertainty
Pain (VAS)
Aligners and fixed labial appliances (combined) vs Within-group change, 7 days versus 24 hours after appliance fit · 24 hours to 7 days
SMD -7.45 [-11.28, -3.62]5 studies · 264 participantsGRADE not reported
Pain (VAS)
Fixed labial appliances vs Within-group change, 7 days versus 24 hours after appliance fit · 24 hours to 7 days
SMD -6.40 [-10.42, -2.38]5 studies · 176 participantsGRADE not reported

The review does not say which of its outcomes this study informs.

Outcome this study informsPooled effectEvidenceCertainty
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 10 days
SMD -0.895 [-1.426, -0.364]1 studyGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · All follow-up durations (1 week to end of treatment)
SMD -0.850 [-0.973, -0.727]16 studies · 856 participantsModerate
Pain intensity
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · All follow-up time points (1 week to 6 months)
SMD -0.419 [-0.536, -0.302]18 studies · 892 participantsModerate
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 3 months
SMD -0.590 [-1.194, 0.013]1 studyGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 2 weeks
SMD -0.734 [-1.172, -0.397]2 studiesGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · End of treatment
SMD -0.970 [-1.412, -0.528]2 studiesGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 20 days
SMD -0.895 [-1.426, -0.364]1 studyGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 1 week
SMD -0.985 [-1.272, -0.699]3 studiesGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 6 months
SMD -0.850 [-1.144, -0.557]4 studiesGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 1 month
SMD -0.829 [-1.081, -0.577]4 studiesGRADE not reported
Quality of life
Clear aligners (Invisalign and similar removable aligners) vs Fixed orthodontic appliances (metal, self-ligating, ceramic, lingual brackets) · 12 months
SMD -0.531 [-1.178, 0.116]1 studyGRADE not reported

3 including reviews in total.