Primary study · included by 1 review
Effect of mixed mutans streptococci colonization on caries development.
Seki 2006 · Seki M, Yamashita Y, Shibata Y, et al. · Oral microbiology and immunology · 2006
PubMed 16390341doi:10.1111/j.1399-302x.2005.00253.xJournal Article; Research Support, Non-U.S. Gov't
Trial PICO
Not extracted yet. Trial-level population, intervention, comparator, outcomes and design will appear here after the trial extraction run. Until then, the reviews below describe the study.
Results
Not extracted yet. Per-trial results (events, means, effect and weight as each review's forest plot reports them) will appear here after the trial extraction run.
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 6 months to 3.5 years | OR 4.13 [3.33, 5.12] | 12 studies · 3010 participants | Moderate |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 6 months to 3.5 years | OR 5.16 [2.99, 8.91] | 5 studies · 736 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 6 months to 3.5 years | OR 3.92 [3.20, 4.80] | 9 studies · 2577 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 1 year | OR 4.37 [3.50, 5.45] | 4 studies · 2016 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 2.7 years (31 months median) | OR 33.00 [3.18, 342.26] | 1 study · 28 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 2 years | OR 2.53 [1.22, 5.23] | 4 studies · 297 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 6 months to 3.5 years | OR 3.82 [2.01, 7.26] | 6 studies · 732 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 3.5 years (42 months) | OR 4.23 [2.49, 7.18] | 1 study · 366 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 6 months | OR 4.65 [2.01, 10.76] | 2 studies · 303 participants | Ungraded |
Development of any (cavitated or non-cavitated) carious lesion Mutans streptococci present in oral samples at baseline vs Mutans streptococci absent in oral samples at baseline · 6 months to 3.5 years | OR 4.36 [3.53, 5.39] | 6 studies · 2278 participants | Ungraded |
1 including review in total.