evidencegaps
Primary study · included by 1 review

Immunohistochemical study on overexpression of cyclooxygenase-2 in squamous cell carcinoma of the oral cavity: its importance as a prognostic predictor.

Itoh 2003 · Itoh Shigeto, Matsui Kazuhiro, Furuta Isao, et al. · Oral oncology · 2003

Included by

Cyclooxygenase-2 (COX-2) as a Potential Prognostic Marker in Oral Squamous Cell Carcinoma: A Systematic Review and Meta-Analysis.
Non-Cochrane · prognostic · 2026 · cited as Itoh 2003 · Figure 2
Outcome this study informsPooled effectEvidenceCertainty
Progression-free survival
High COX-2 expression (immunohistochemistry) vs Low COX-2 expression
HR 1.86 [1.21, 2.87]3 studiesGRADE not reported
Overall survival
High COX-2 expression (immunohistochemistry) vs Low COX-2 expression
HR 1.49 [1.06, 2.1]8 studiesGRADE not reported

1 including review in total.