Primary study · included by 1 review

Talwar S 2020

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Comparative efficacy of novel biomaterials versus traditional materials in the treatment of dental and pulpal diseases: a systematic review and meta-analysis.

Non-Cochrane · intervention · 2026 · cited as Talwar S 2020 · Supplementary Table 5

Outcome this study informs	Pooled effect	Evidence	Certainty
Clinical and radiographic success rate Bioceramic (calcium silicate) sealer, single-cone obturation (e.g., iRoot SP, Bio-C Sealer, C-Root SP) vs Epoxy resin-based sealer (AH Plus) · 6-24 months	OR 1.12 [0.85, 1.47]	6 studies · 612 participants	GRADE not reported
Apical sealing ability / microleakage Bioceramic (calcium silicate) sealer, single-cone obturation (e.g., iRoot SP, Bio-C Sealer, C-Root SP) vs Epoxy resin-based sealer (AH Plus)	SMD -2.35	6 studies	GRADE not reported
Clinical and radiographic success rate Bioceramic (calcium silicate) sealer, single-cone obturation (e.g., iRoot SP, Bio-C Sealer, C-Root SP) vs Epoxy resin-based sealer (AH Plus) · 6-24 months	OR 1.41 [0.85, 2.34]	6 studies · 612 participants	GRADE not reported
Retreatment difficulty Bioceramic (calcium silicate) sealer, single-cone obturation (e.g., iRoot SP, Bio-C Sealer, C-Root SP) vs Epoxy resin-based sealer (AH Plus)	SMD 1.52 [1.20, 1.84]	3 studies · 238 participants	GRADE not reported
Apical sealing ability / microleakage Bioceramic (calcium silicate) sealer, single-cone obturation (e.g., iRoot SP, Bio-C Sealer, C-Root SP) vs Epoxy resin-based sealer (AH Plus)	SMD -1.35 [-1.78, -0.92]	6 studies	GRADE not reported
Retreatment difficulty Bioceramic (calcium silicate) sealer, single-cone obturation (e.g., iRoot SP, Bio-C Sealer, C-Root SP) vs Epoxy resin-based sealer (AH Plus)	SMD 0.88 [0.25, 1.51]	3 studies	GRADE not reported

1 including review in total.