Primary study · included by 1 review

Kumararama 2024

ProbableThe reviews cited this study without a PMID, DOI or NCT, so it is matched by first author and year. Two different studies by the same author in the same year could be merged here.

Included by

Efficacy of adjunctive antibiotics compared to non-antibiotic therapies following mechanical debridement for peri-implantitis: A systematic review and meta-analysis of randomized controlled trials.

Non-Cochrane · intervention · 2026 · cited as Kumararama 2024 · Table 1; Fig 2-5; S3 Fig; S4 Fig

Outcome this study informs	Pooled effect	Evidence	Certainty
Modified plaque index (mPLI) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other) · 3 months	MD -0.13 [-0.27, 0.02]	3 studies · 317 participants	GRADE not reported
Modified plaque index (mPLI) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other)	MD -0.07 [-0.16, 0.01]	7 studies · 477 participants	GRADE not reported
Probing pocket depth (PPD, mm) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other) · 3 months	MD -0.93 [-1.54, -0.32]	7 studies · 571 participants	GRADE not reported
Probing pocket depth (PPD, mm) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other)	MD -0.69 [-1.04, -0.33]	20 studies · 1076 participants	Moderate
Modified plaque index (mPLI) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other) · 6 months	MD -0.01 [-0.15, 0.13]	3 studies · 120 participants	GRADE not reported
Probing pocket depth (PPD, mm) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other) · 12 months	MD -0.84 [-1.25, -0.42]	8 studies · 262 participants	GRADE not reported
Probing pocket depth (PPD, mm) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other)	MD -0.686	20 studies	GRADE not reported
Probing pocket depth (PPD, mm) Mechanical debridement plus adjunctive antibiotics (local or systemic) vs Mechanical debridement alone or with a non-antibiotic adjunct (probiotics, photodynamic therapy, antiseptic or other) · 6 months	MD -0.11 [-0.59, 0.37]	5 studies · 243 participants	GRADE not reported

1 including review in total.