Primary study · included by 1 review

Analysis of the Effects of IL-6 -572 C/G, CRP -757 A/G, and CRP -717 T/C Gene Polymorphisms; IL-6 Levels; and CRP Levels on Chronic Periodontitis in Coronary Artery Disease in Indonesia

Sitompul 2023 · Sitompul Sanggap Indra, Pikir Budi Susetyo, Aryati, et al. · Genes · 2023

Included by

Decoding the periodontitis-coronary artery disease axis through biomarker profiling: a systematic review and meta-analysis.

Non-Cochrane · aetiology · 2026 · cited as Sitompul 2023 · Table 1; Fig. 3 and Fig. 5

Outcome this study informs	Pooled effect	Evidence	Certainty
Interleukin-6 level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.166 [-0.111, 0.443]	3 studies	GRADE not reported
C-reactive protein level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.573 [0.065, 1.082]	5 studies	GRADE not reported
C-reactive protein level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.3930	5 studies	GRADE not reported
C-reactive protein level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.501 [0.275, 0.728]	5 studies	GRADE not reported
Interleukin-6 level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.1424 [-0.0769, 0.3616]	3 studies	GRADE not reported
C-reactive protein level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.3708	5 studies	GRADE not reported
Interleukin-6 level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.166 [-0.111, 0.443]	3 studies	GRADE not reported
Interleukin-6 level Periodontitis with CAD or cardiovascular risk indicators (exposure) vs Controls without periodontitis and/or without CAD or cardiovascular risk indicators · Baseline	SMD 0.1424 [-0.0769, 0.3616]	3 studies	GRADE not reported

1 including review in total.