Primary study · included by 1 review

Nanosilicate-functionalized nanofibrous membrane facilitated periodontal regeneration potential by harnessing periodontal ligament cell-mediated osteogenesis and immunomodulation

X. Xu 2023 · Xu Xiongcheng, Chen Ziqin, Xiao Long, et al. · Journal of Nanobiotechnology · 2023

Included by

Polycaprolactone Scaffolds for BONE Regeneration in Animal Models of Cranial Defects: A Systematic Review and Meta-Analysis
Non-Cochrane · intervention · 2026 · cited as X. Xu 2023 · Figures 2-4; Table 4; reference [36]
Outcome this study informsPooled effectEvidenceCertainty
Bone regeneration (BV/TV, %) at 1-2 months (middle stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle)
QM = 0.019, df = 1, p = 0.891, R2 = 0%27 studiesGRADE not reported
Bone regeneration (BV/TV, %) at 1-2 months (middle stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle)
QM = 0.148, df = 1, p = 0.701, R2 = 0%27 studiesGRADE not reported
Bone regeneration (BV/TV, %) at 1-2 months (middle stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle)
QM = 3.742, df = 2, p = 0.154, R2 = 6.4%27 studiesGRADE not reported
Bone regeneration (BV/TV, %) at 1-2 months (middle stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle)
MD 5.6 [3.48, 7.72]25 studies · 260 participantsGRADE not reported
Bone regeneration (BV/TV, %) at 1-2 months (middle stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle)
Meta-regression beta (difference in MD, %) 10.748 [-0.505, 22.001]27 studiesGRADE not reported
Bone regeneration (BV/TV, %) at 1-2 months (middle stage)
Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle)
Meta-regression beta (difference in MD, %) 1.677 [-3.37, 6.723]27 studiesGRADE not reported

1 including review in total.