Primary study · included by 1 review
High Mobility Group Box-1 (HMGB1)/microRNA-155 Axis in the Pathogenesis of Type 2 Diabetes Mellitus Associated Periodontitis: A Case Control Study
Appukuttan 2025 · Appukuttan Devapriya, Subramanian Sangeetha, Prakash P. S. G., et al. · Journal of Advanced Oral Research · 2025
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.814 | 4 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.85 | 2 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.85 [0.77, 0.91] | 5 studies | Moderate |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.841 | 4 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.84 | 5 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.83 | 3 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.860 | 4 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.829 | 4 studies | GRADE not reported |
Pooled sensitivity miR-155 expression level as index test (qPCR) vs Reference standard: clinical or radiographic periodontitis criteria (CAL, PPD, radiographic bone loss) | Sensitivity 0.850 | 4 studies | GRADE not reported |
1 including review in total.