Primary study · included by 1 review

Efficacy of low-level laser therapy for the treatment of burning mouth syndrome: a randomized, controlled trial

Spanemberg 2015 · Spanemberg Juliana Cassol, López José, de Figueiredo Maria Antonia Zancanaro, et al. · Journal of Biomedical Optics · 2015

Included by

Advanced, pharmacological and complementary interventions for chronic or recurrent orofacial pain conditions: a systematic evidence map with selective meta-analyses.
Non-Cochrane · intervention · 2026 · cited as Spanemberg 2015 · Reference list (ref 89); Supplementary Table 4
Outcome this study informsPooled effectEvidenceCertainty
Pain intensity
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -1.00 [-1.98, -0.02]2 studiesGRADE not reported
Pain intensity
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -1.00 [-1.98, -0.03]NRGRADE not reported
Quality of life
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.74 [-1.30, -0.17]2 studiesGRADE not reported
Pain intensity
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.75 [-1.24, -0.26]3 studiesGRADE not reported
Quality of life
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.35 [-0.91, 0.21]1 studyGRADE not reported
Quality of life
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.82 [-1.42, -0.21]2 studies · 156 participantsLow
Quality of life
Photobiomodulation / low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate to 4 weeks)
SMD -0.82 [-1.42, -0.21]2 studies · 156 participantsGRADE not reported
Pain intensity
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.42 [-0.67, -0.16]2 studiesGRADE not reported
Pain intensity
Photobiomodulation / low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate to 4 weeks)
SMD -0.76 [-1.09, -0.43]3 studies · 200 participantsGRADE not reported
Pain intensity
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.86 [-1.44, -0.29]2 studiesGRADE not reported
Quality of life
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -1.16 [-2.20, -0.11]1 studyGRADE not reported
Pain intensity
Photobiomodulation / low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate to 4 weeks)
SMD -0.81 [-1.35, -0.27]3 studies · 200 participantsGRADE not reported
Quality of life
Photobiomodulation / low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate to 4 weeks)
SMD -0.81 [-1.20, -0.42]2 studies · 156 participantsGRADE not reported
Pain intensity
Photobiomodulation or low-level laser therapy (PBM/LLLT) vs Inactive control (placebo, sham, usual care or no intervention) · Short-term (immediate post-intervention to 4 weeks)
SMD -0.81 [-1.35, -0.27]3 studies · 200 participantsModerate

1 including review in total.