Primary study · included by 1 review
Multikingdom oral microbiome interactions in early-onset cryptogenic ischemic stroke
Manzoor 2024 · Manzoor Muhammed, Leskelä Jaakko, Pietiäinen Milla, et al. · ISME Communications · 2024
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Bacteroidota relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.36 [0.18, 0.54] | 3 studies · 499 participants | Low |
Proteobacteria (Pseudomonadota) relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD -0.48 [-1.02, 0.06] | 3 studies · 499 participants | Low |
Actinomycetota relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD -0.04 [-0.24, 0.17] | 2 studies · 368 participants | Low |
Bacteroidota relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.62 | 2 studies | GRADE not reported |
Proteobacteria (Pseudomonadota) relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD -0.68 | 2 studies | GRADE not reported |
Fusobacteriota relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD -0.1 [-0.46, 0.27] | 3 studies · 499 participants | Very low |
Bacteroidota relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.43 [0.14, 0.71] | 3 studies · 499 participants | Low |
Shannon alpha diversity Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.18 [-0.04, 0.4] | 9 studies | GRADE not reported |
Observed species alpha diversity Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.13 [-0.06, 0.33] | 6 studies | GRADE not reported |
Shannon alpha diversity Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.31 [0.02, 0.61] | 10 studies · 1241 participants | Low |
Observed species alpha diversity Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD 0.39 [0.05, 0.72] | 7 studies · 1099 participants | Low |
Proteobacteria (Pseudomonadota) relative abundance Stroke (oral microbiota of stroke patients) vs Healthy adult controls without history of stroke · Single oral sample; collection from 24 h to 3 months after stroke (varies by study) | SMD -0.26 [-0.44, -0.07] | 3 studies · 499 participants | Low |
1 including review in total.