evidencegaps
Primary study · included by 1 review

Levels of high-mobility group box-1 in gingival crevicular fluid in nonsmokers and smokers with chronic periodontitis

Lin 2017 · Lin Yi-Chun, Wu Ching-Yi, Chang Lien-Yu, et al. · Journal of the Formosan Medical Association · 2017

Included by

A study on the association between smoking, periodontal inflammation and alveolar bone resorption in patients with chronic periodontitis based on biomarkers: a meta-analysis.
Non-Cochrane · aetiology · 2025 · cited as Lin 2017 · Figure 3; Table 1
Outcome this study informsPooled effectEvidenceCertainty
Interleukin-17 (IL-17) level in gingival crevicular fluid
Smoking (smoker chronic periodontitis patients) vs Non-smoker chronic periodontitis patients
MD 94.62 [23.34, 165.90]3 studies · 174 participantsGRADE not reported
High-mobility group box 1 (HMGB1) level in gingival crevicular fluid
Smoking (smoker chronic periodontitis patients) vs Non-smoker chronic periodontitis patients
MD 6.02 [1.30, 10.73]3 studies · 130 participantsGRADE not reported

1 including review in total.