Primary study · included by 1 review
Decellularized extracellular matrix coupled with polycaprolactone/laponite to construct a biomimetic barrier membrane for bone defect repair
M. He 2024 · He Mengjiao, Li Lisheng, Liu Yijuan, et al. · International Journal of Biological Macromolecules · 2024
Included by
| Outcome this study informs | Pooled effect | Evidence | Certainty |
|---|---|---|---|
Bone regeneration (BV/TV, %) at 1-2 months (middle stage) Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle) | QM = 0.019, df = 1, p = 0.891, R2 = 0% | 27 studies | GRADE not reported |
Bone regeneration (BV/TV, %) at 1-2 months (middle stage) Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle) | QM = 0.148, df = 1, p = 0.701, R2 = 0% | 27 studies | GRADE not reported |
Bone regeneration (BV/TV, %) at 1-2 months (middle stage) Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle) | QM = 3.742, df = 2, p = 0.154, R2 = 6.4% | 27 studies | GRADE not reported |
Bone regeneration (BV/TV, %) at 1-2 months (middle stage) Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle) | MD 5.6 [3.48, 7.72] | 25 studies · 260 participants | GRADE not reported |
Bone regeneration (BV/TV, %) at 1-2 months (middle stage) Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle) | Meta-regression beta (difference in MD, %) 10.748 [-0.505, 22.001] | 27 studies | GRADE not reported |
Bone regeneration (BV/TV, %) at 1-2 months (middle stage) Polycaprolactone (PCL)-only scaffold vs Empty defect · 1-2 months (middle) | Meta-regression beta (difference in MD, %) 1.677 [-3.37, 6.723] | 27 studies | GRADE not reported |
1 including review in total.