evidencegaps
Primary study · included by 1 review

The association between frailty and incident cardiovascular disease events in community-dwelling healthy older adults

Ekram 2023 · Ekram A.R.M. Saifuddin, Tonkin Andrew M., Ryan Joanne, et al. · American Heart Journal Plus: Cardiology Research and Practice · 2023

Included by

Association of frailty and mortality risk in community-dwelling older adults: a systematic review and meta-analysis of 59 international prospective cohort studies.
Non-Cochrane · prognostic · 2026 · cited as Ekram 2023 · Table 1; reference 46
Outcome this study informsPooled effectEvidenceCertainty
All-cause mortality
Non-robust (frail, prefrail or equivalent) on any frailty instrument vs Robust (no signs of frailty) · Follow-up 1 to 15 years
HR 1.83 [1.70, 1.97]56 studiesGRADE not reported
All-cause mortality
Non-robust (frail, prefrail or equivalent) on any frailty instrument vs Robust (no signs of frailty) · Follow-up 1 to 15 years
HR 1.11 [1.11, 1.29]NRGRADE not reported
All-cause mortality
Non-robust (frail, prefrail or equivalent) on any frailty instrument vs Robust (no signs of frailty) · Follow-up 1 to 15 years
HR 1.46 [1.27, 1.68]NRGRADE not reported

1 including review in total.