evidencegaps
Primary study · included by 3 reviews

Harvest graft substitute for soft tissue volume augmentation around existing implants: A randomized, controlled and blinded multicenter trial

ClemDS 2024 · Clem Donald S., McClain Pamela K., McGuire Michael K., et al. · Journal of Periodontology · 2023

Included by

Comparative outcomes of xenogeneic collagen matrices and autogenous graft-based techniques to increase mucosal thickness and keratinised mucosa width at implant sites: are autologous grafts still the gold standard? A systematic review and meta-analysis of randomised clinical trials.
Non-Cochrane · intervention · 2026 · cited as Clem 2024 · Results, Study selection; Figures 2-4 and 6; reference list
Outcome this study informsPooled effectEvidenceCertainty
Increase in buccal mucosal thickness (MT), mm
Crosslinked xenogeneic collagen matrix (VCMX, Fibro-Gide) with bilaminar technique vs Subepithelial connective tissue graft (CTG) with bilaminar technique · 3 months
MD 0.02 [-0.17, 0.22]4 studies · 142 participantsGRADE not reported
Increase in buccal mucosal thickness (MT), mm
Xenogeneic collagen matrices (XCM*, non-crosslinked, and VCMX, crosslinked) with bilaminar technique vs Subepithelial connective tissue graft (CTG) with bilaminar technique · 3 months
MD 0.27 [0.12, 0.42]9 studies · 294 participantsGRADE not reported
Emerging, personalized, and minimally invasive technologies for periodontal and peri-implant soft and hard tissue regenerative therapy.
Non-Cochrane · intervention · 2026 · cited as Clem 2024 · Table 2 (reference 113)

The review does not say which of its outcomes this study informs.

Autogenous grafts versus substitute scaffolds for soft tissue augmentation in implant therapy: A systematic review.
Non-Cochrane · intervention · 2026 · cited as Clem 2024 · References 34

The review does not say which of its outcomes this study informs.

3 including reviews in total.