Topic in Oral Health
Oral medicine and oral cancer
Oral cancer and potentially malignant disorders, mucosal disease, dry mouth, and taste disorders.
34 systematic reviews in Oral medicine and oral cancer ask 1,325 questions. 12.4% have no studies to answer them, 15.8% rest on very low certainty evidence and 3% reach moderate or high certainty.
Reviews
34
Questions
1,325
current versions
No studies
12.4%
Moderate or high
3%
No studies 164 · 12.4%Ungraded 841 · 63.5%Very low 209 · 15.8%Low 72 · 5.4%Moderate 38 · 2.9%High 1 · 0.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Thinnest evidence
All no studies and very low questions| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Antioxidants (lycopene, curcumin, Oxitard) vs Placebo or no active treatment Hospital admission (length of stay) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) Interventions for managing oral submucous fibrosis (2024) · Cochrane | The trials did not measure hospital admission. | 0 studies | No studies |
Physiotherapy (tongue-spatula jaw exercises) vs No active treatment Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · 3 to 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 0.50 [-7.72, 8.72] | 1 study · 24 participants | Very low |
Topical curcumin gel vs Topical aloe vera gel Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · Less than 3 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD -0.64 [-3.91, 2.63] | 1 study · 60 participants | Very low |
Buccal fat pad pedicle plus placental extract vs Buccal fat pad pedicle alone Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · Less than 3 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 7.80 [4.90, 10.70] | 1 study · 10 participants | Very low |
Antioxidants (lycopene, curcumin, Oxitard) vs Placebo or no active treatment Participant-reported resumption of normal eating, chewing and speech · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) Interventions for managing oral submucous fibrosis (2024) · Cochrane | SoF: participant-reported resumption of normal eating, chewing and speech - outcome not reported by included studies. | 0 studies | No studies |
Vasodilators (isoxsuprine, xanthinol nicotinate) vs Placebo or no active treatment Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · 3 to 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 4.04 [-1.93, 10.02] | 2 studies · 85 participants | Very low |
Buccal fat pad graft vs Extended nasolabial flap Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · More than 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 6.50 [-10.72, 23.72] | 1 study · 8 participants | Very low |
Pentoxifylline vs Spirulina Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · 3 to 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 0.50 [-6.60, 7.60] | 1 study · 40 participants | Very low |
Buccal fat pad graft vs Extended nasolabial flap Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · Less than 3 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD -7.25 [-14.19, -0.31] | 1 study · 8 participants | Very low |
Surgery plus Heister jaw opener vs Surgery plus wooden tongue depressors Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · More than 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 0.60 [0.01, 1.19] | 1 study · 50 participants | Very low |
Abdominal dermal fat graft vs Nasolabial flap Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · 3 to 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD -14.87 [-19.93, -9.81] | 1 study · 30 participants | Very low |
Buccal fat pad graft vs Extended nasolabial flap Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) · 3 to 6 months Interventions for managing oral submucous fibrosis (2024) · Cochrane | MD 6.00 [-11.36, 23.36] | 1 study · 8 participants | Very low |
Reviews 34
Interventions for treating oral candidiasis for patients with cancer receiving treatment
Cochranefull textintervention
22 questions
Interventions for treating oral mucositis for patients with cancer receiving treatment
Cochranefull textintervention
52 questions
Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy
Cochranefull textintervention
47 questions
Interventions for the prevention and treatment of herpes simplex virus in patients being treated for cancer
Cochranefull textintervention
22 questions
Acyclovir for treating primary herpetic gingivostomatitis
Cochranefull textintervention
11 questions
Mouthrinses for the treatment of halitosis
Cochranefull textintervention
16 questions
Interventions for the management of submucous cleft palate
Cochranefull textintervention
8 questions
Interventions for preventing oral candidiasis for patients with cancer receiving treatment
Cochranefull textintervention
43 questions
Tongue scraping for treating halitosis
Cochranefull textintervention
5 questions