Non-Cochrane · intervention · PM42421792
Effect of the multiple sutures and suture-less wound closure on the wound healing after surgical extraction of the mandibular third molars: a systematic review and metaanalysis.
Pande Somya, Londhe Uday, Bhate Kalyani, et al. · Frontiers in oral health · 2026 · PubMed · doi:10.3389/froh.2026.1842421
Findings
Population Patients undergoing surgical extraction of mandibular third molars
3 findings
| Suture-less wound closure | Multiple-suture wound closure | Pain 48 hours | SMD -0.46 [-1.38, 0.46] Low Downgraded: risk of bias, imprecision, inconsistency 4 studies · 264 participants |
| Suture-less wound closure | Multiple-suture wound closure | Facial swelling 48 hours | SMD -0.56 [-1.35, 0.22] Low Downgraded: risk of bias, imprecision, inconsistency 3 studies · 190 participants |
| Suture-less wound closure | Multiple-suture wound closure | Trismus 7 days | SMD -0.38 [-0.83, 0.06] Low Downgraded: risk of bias, imprecision, inconsistency 4 studies · 252 participants |
Included primary studies 10
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Alkadi 2019 Effect of One-Suture and Sutureless Techniques on Postoperative Healing After Third Molar Surgery. PMID:30611694 | 2019 | this review only | not stated | not extracted yet |
| Chukwuma 2022 Postoperative Sequelae Following Surgical Extraction of Impacted Mandibular Third-Molar Extraction Using the Complete Closure Versus the… PMID:36590767 | 2022 | this review only | Pain; Trismus | not extracted yet |
| Gay-Escoda 2015 Effect of the suture technique on postoperative pain, swelling and trismus after removal of lower third molars: A randomized clinical trial. PMID:25662551 | 2015 | this review only | not stated | not extracted yet |
| Hashemi 2012 The effect of sutureless wound closure on postoperative pain and swelling after impacted mandibular third molar surgery. PMID:21636189 | 2012 | this review only | not stated | not extracted yet |
| Katta 2018 DOI:10.21276/ijmrp.2018.4.3.009 | NR | this review only | Pain; Facial swelling; Trismus | not extracted yet |
| Mahat 2020 A Comparative Study of the Effect of Sutureless Versus Multiple Sutures Technique on Complications following Third Molar Surgery in… PMID:32104180 | 2020 | this review only | Trismus | not extracted yet |
| Osunde 2011 Comparative study of effect of single and multiple suture techniques on inflammatory complications after third molar surgery. PMID:20950914 | 2011 | this review only | Pain; Facial swelling; Trismus | not extracted yet |
| Osunde 2012 A comparative study of the effect of suture-less and multiple suture techniques on inflammatory complications following third molar surgery. PMID:22591717 | 2012 | this review only | Pain; Facial swelling; Trismus | not extracted yet |
| Rodrigues 2023 Comparison of two suture techniques on the inflammatory signs after third molars extraction-A randomized clinical trial. PMID:37352294 | 2023 | this review only | not stated | not extracted yet |
| Takadoum 2022 Sutureless socket technique after removal of third molars: a multicentric, open, randomized controlled trial. PMID:35754043 | 2022 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients requiring surgical extraction of mandibular third molars | Patients after surgical extraction of mandibular third molars (n=556 across 10 RCTs) |
| Intervention | Sutureless wound closure | Suture-less closure |
| Comparison | Closure with suture | Multiple-suture (or single-suture) closure |
| Outcomes | Primary: swelling, infection, trismus, wound dehiscence (pain, facial swelling, trismus pooled); secondary: bleeding, postoperative complications | Pain at 48 h (4 RCTs, n=264); facial swelling at 48 h (3 RCTs, n=190); trismus at 7 days (4 RCTs, n=252); bleeding and complications narrative |
| Study designs | RCTs only | RCTs (n=10) |
| Timing | Not specified | 48 hours to 7 days (some trials up to 1 month) |