Non-Cochrane · intervention · PM42271364
The application of artificial intelligence in the field of dental restoration for designing dental crowns: a meta-analysis.
Hu Jiaxuan, Bai Binding, Wang Yuzhou, et al. · BMC oral health · 2026 · PubMed · doi:10.1186/s12903-026-08680-1
Findings
Population Dental crowns (in vitro)
4 findings
| AI-designed dental crowns | Traditional CAD-based dental crowns | Occlusal accuracy | MD -67.39 [-132.36, -2.42] GRADE not reported 3 studies · 106 participants |
| AI-designed dental crowns | Traditional CAD-based dental crowns | Design time | MD -289.03 [-450.18, -127.88] GRADE not reported 5 studies · 256 participants |
| AI-designed dental crowns | Traditional CAD-based dental crowns | Occlusal morphology discrepancy | MD -0.02 [-0.06, 0.02] GRADE not reported 4 studies · 176 participants |
| AI-designed dental crowns | Traditional CAD-based dental crowns | Cusp angle | MD 3.31 [1.12, 5.5] GRADE not reported 3 studies · 108 participants |
Included primary studies 11
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Chen 2022 Morphology and fracture behavior of lithium disilicate dental crowns designed by human and knowledge-based AI. PMID:35508087 | 2022 | 1 other review | Occlusal morphology discrepancy; Cusp angle | not extracted yet |
| Cho 2024 Tooth morphology, internal fit, occlusion and proximal contacts of dental crowns designed by deep learning-based dental software: A… PMID:38163455 | 2024 | 1 other review | Cusp angle | not extracted yet |
| Ding 2023 Morphology and mechanical performance of dental crown designed by 3D-DCGAN. PMID:36822895 | 2023 | 1 other review | Cusp angle | not extracted yet |
| Liu CM 2025 Evaluation of the accuracy, occlusal contact and clinical applications of zirconia crowns using artificial intelligence design versus… PMID:40654460 | 2025 | 1 other review | Occlusal accuracy | not extracted yet |
| Nagata 2025 Verification of the accuracy and design time of crowns designed with artificial intelligence. PMID:40061025 | 2025 | 1 other review | Design time; Occlusal accuracy | not extracted yet |
| Wu 2025 Comparison of the Efficacy of Artificial Intelligence-Powered Software in Crown Design: An In Vitro Study. PMID:39069456 | 2025 | 1 other review | Design time; Occlusal accuracy | not extracted yet |
| Ender 2011 Efficiency of a mathematical model in generating CAD/CAM-partial crowns with natural tooth morphology. PMID:20143242 | 2011 | this review only | Design time | not extracted yet |
| Kollmuss 2013 Comparison of biogenerically reconstructed and waxed-up complete occlusal surfaces with respect to the original tooth morphology. PMID:22580927 | 2013 | this review only | Occlusal morphology discrepancy | not extracted yet |
| Kollmuss 2016 Comparison of chairside and laboratory CAD/CAM to conventional produced all-ceramic crowns regarding morphology, occlusion, and aesthetics. PMID:26245275 | 2016 | this review only | Occlusal morphology discrepancy | not extracted yet |
| Litzenburger 2013 Fully automatic CAD design of the occlusal morphology of partial crowns compared to dental technicians' design. PMID:22451342 | 2013 | this review only | Occlusal morphology discrepancy | not extracted yet |
| Liu CM 2024 Evaluation of the efficiency, trueness, and clinical application of novel artificial intelligence design for dental crown prostheses. PMID:37858418 | 2024 | this review only | Design time | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Accuracy and Functional Performance of Artificial Intelligence-Based Automated Crown Design Systems: A Systematic Review and Meta-Analysis. (2026) | 6 | 0.27 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Dental crowns | Dental crowns (in vitro; n=12 studies) |
| Intervention | AI-designed dental crowns | AI-designed dental crowns |
| Comparison | Traditional CAD-based dental crowns | Traditional CAD-based dental crowns |
| Outcomes | Design time; occlusal morphology discrepancy; occlusal accuracy; cusp angle | Design time (5 studies); occlusal morphology discrepancy (4); occlusal accuracy (3); cusp angle (3) |
| Study designs | In vitro studies | In vitro studies (n=12) |
| Timing | Not specified | Not specified |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | No | Partial Yes | no |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | No | No | yes |
| 8Included studies described in detail | No | No | yes |
| 9Risk of bias assessed satisfactorilycritical | NRSI: Partial Yes · RCT: N/A | NRSI: Partial Yes · RCT: N/A | yes |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: N/A · NRSI: No | NRSI: Yes · RCT: N/A | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | No | No | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | No | No | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |