Non-Cochrane · intervention · PM42204530

The efficacy of piezocision in accelerating leveling and alignment of anterior teeth in extraction and non-extraction treatments: a systematic review and meta-analysis.

Al-Bitar Mohammad Abdalbaset T, Hajeer Mohammad Y, Burhan Ahmad S, et al. · BMC oral health · 2026 · PubMed · doi:10.1186/s12903-026-08712-w

Findings

7 findings

Population
Adults (over 17 years) with crowded anterior teeth undergoing orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationPostoperative pain or discomfort
Various
Studies used different pain scales, and one study (Sultana et al., 2022) lacked a control group (No Comparison), preventing data pooling.
Very low
Downgraded: risk of bias, imprecision, inconsistency
3 studies · 50 participants
Adults (over 17 years) with crowded anterior teeth undergoing orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationOverall orthodontic treatment time (days)
Until completion of orthodontic treatment · All three studies
MD -262.68 [-429.96, -95.39]
Low
Downgraded: risk of bias, inconsistency
3 studies · 72 participants
Adults (over 17 years) with crowded anterior teeth undergoing orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationOverall orthodontic treatment time (days)
Until completion of orthodontic treatment · Sensitivity analysis excluding Strippoli 2019
MD -170.23 [-282.47, -57.99]
GRADE not reported
2 studies · 48 participants
Adults (over 17 years) with crowded anterior teeth undergoing orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationLeveling and alignment duration of anterior teeth (days)
Until completion of leveling and alignment · All studies (before subgroup analysis)
MD -56.31 [-74.00, -38.63]
GRADE not reported
7 studies
Adults with crowded anterior teeth in non-extraction orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationLeveling and alignment duration of anterior teeth (days)
Until completion of leveling and alignment · Non-extraction cases
MD -24.06 [-51.54, 3.42]
Very low
Downgraded: risk of bias, imprecision, inconsistency
3 studies · 62 participants
Adults with crowded anterior teeth in extraction orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationLeveling and alignment duration of anterior teeth (days)
Until completion of leveling and alignment · Extraction cases, after sensitivity analysis (Sultana 2022 excluded)
MD -79.80 [-85.21, -74.38]
High
3 studies · 104 participants
Adults with crowded anterior teeth in extraction orthodontic treatmentPiezocision-assisted corticotomy plus orthodontic treatmentConventional orthodontic treatment without accelerationLeveling and alignment duration of anterior teeth (days)
Until completion of leveling and alignment · Extraction cases, before sensitivity analysis
MD -69.70 [-85.24, -54.16]
GRADE not reported
4 studies · 117 participants

Included primary studies 9

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Charavet 2019
Piezocision-assisted orthodontic treatment using CAD/CAM customized orthodontic appliances: a randomized controlled trial in adults
DOI:10.1093/ejo/cjy082
20191 other reviewnot statednot extracted yet
Gibreal 2019
Efficacy of piezocision-based flapless corticotomy in the orthodontic correction of severely crowded lower anterior teeth: a randomized…
DOI:10.1093/ejo/cjy042
20181 other reviewnot statednot extracted yet
Sultana 2022
Effect of piezocision procedure in levelling and alignment stage of fixed orthodontic treatment: a randomized clinical trial
DOI:10.1038/s41598-022-09851-0
20221 other reviewnot statednot extracted yet
Uribe 2017
Efficiency of piezotome-corticision assisted orthodontics in alleviating mandibular anterior crowding—a randomized clinical trial
DOI:10.1093/ejo/cjw091
20171 other reviewnot statednot extracted yet
Al-Ibrahim 2022
Leveling and alignment time and the periodontal status in patients with severe upper crowding treated by corticotomy-assisted…
DOI:10.1016/j.ejwf.2021.09.002
2022this review onlynot statednot extracted yet
Charavet 2016
Localized Piezoelectric Alveolar Decortication for Orthodontic Treatment in Adults
DOI:10.1177/0022034516645066
2016this review onlynot statednot extracted yet
Gibreal 2023
The efficacy and accuracy of 3D-guided orthodontic piezocision: a randomized controlled trial
DOI:10.1186/s12903-023-02902-6
2023this review onlynot statednot extracted yet
Mehr 2013
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Strippoli 2019
Piezocorticision-assisted orthodontics: Efficiency, safety, and long-term evaluation of the inflammatory process
DOI:10.1016/j.ajodo.2018.06.013
2019this review onlynot statednot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationAdults over 17 years undergoing orthodontic treatment with crowded anterior teeth (Little irregularity index at least 5 mm)Adults with anterior crowding (n=246)
InterventionPiezocision-assisted corticotomy with conventional orthodontic treatmentFlapless piezocision with fixed appliances (n=114)
ComparisonConventional orthodontic treatment without any acceleration methodConventional orthodontic treatment (n=132)
OutcomesTime to level and align crowded anterior teeth; secondary: pain or discomfortLeveling and alignment duration (7 studies); overall treatment time (3 studies); pain (3 studies, not pooled)
Study designsRandomized, non-randomized clinical trials and cohort studies8 RCTs and 1 non-randomized controlled trial (n=9)
TimingNot specifiedFollow-up until completion of alignment or of orthodontic treatment