Non-Cochrane · intervention · PM41984346
Meta-analysis of laser-assisted periodontal therapy (2015-2025).
Sunar Ayşegül, Sır Eda, Taş Çağan, et al. · Lasers in medical science · 2026 · PubMed · doi:10.1007/s10103-026-04866-9
Findings
Population Patients with chronic or generalized periodontitis
1 finding
| Adjunctive Er:YAG laser with scaling and root planing | Scaling and root planing alone | Clinical attachment level (CAL) gain 0 to 6 months · Er:YAG laser; 4-6 mm pockets | MD 0.319 [-0.097, 0.735] Moderate Downgraded: imprecision Studies not reported |
Included primary studies 26
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Abdulsamee 2017 All Tissues Dental Laser Er:YAG laser- Review Article DOI:10.26717/bjstr.2017.01.000104 | 2017 | 1 other review | not stated | not extracted yet |
| Al Asmari 2025 Laser Technology in Periodontal Treatment: Benefits, Risks, and Future Directions-A Mini Review. PMID:40142770 | 2025 | this review only | not stated | not extracted yet |
| Aldelaimi 2015 Clinical Application of Diode Laser (980 nm) in Maxillofacial Surgical Procedures DOI:10.1097/scs.0000000000001727 | 2015 | this review only | not stated | not extracted yet |
| Alfergany 2019 Calculus Removal and Root Surface Roughness When Using the Er:YAG or Er,Cr:YSGG Laser Compared with Conventional Instrumentation Method: A… DOI:10.1089/photob.2018.4465 | 2019 | this review only | not stated | not extracted yet |
| Aoki 2015 Periodontal and peri‐implant wound healing following laser therapy DOI:10.1111/prd.12080 | 2015 | this review only | not stated | not extracted yet |
| Basil 2017 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Chambrone 2018 (aPDT) DOI:10.1902/jop.2017.170172 | NR | this review only | not stated | not extracted yet |
| Chambrone 2018 (infrared lasers) DOI:10.1902/jop.2017.160504 | NR | this review only | not stated | not extracted yet |
| Cobb 2017 Lasers and the treatment of periodontitis: the essence and the noise DOI:10.1111/prd.12137 | 2017 | this review only | not stated | not extracted yet |
| D'Albis 2025 Adjunctive Effects of Diode Laser in Surgical Periodontal Therapy: A Narrative Review of the Literature DOI:10.3390/oral5010013 | 2025 | this review only | not stated | not extracted yet |
| Daggett 2020 Laser Safety: The Need for Protocols DOI:10.12788/cutis.0025 | 2020 | this review only | not stated | not extracted yet |
| Dobrzanski 2020 The Concept of Sustainable Development of Modern Dentistry DOI:10.3390/pr8121605 | 2020 | this review only | not stated | not extracted yet |
| Grzech-Lesniak 2018 Laser reduction of specific microorganisms in the periodontal pocket using Er:YAG and Nd:YAG lasers: a randomized controlled clinical study DOI:10.1007/s10103-018-2491-z | 2018 | this review only | not stated | not extracted yet |
| Jacobs 2024 Radiographic diagnosis of periodontal diseases – Current evidence versus innovations DOI:10.1111/prd.12580 | 2024 | this review only | not stated | not extracted yet |
| Kawamura 2020 <i>Ex Vivo</i> Evaluation of Gingival Ablation with Various Laser Systems and Electroscalpel DOI:10.1089/photob.2019.4713 | 2020 | this review only | not stated | not extracted yet |
| Kwon 2021 Current Concepts in the Management of Periodontitis DOI:10.1111/idj.12630 | 2021 | this review only | not stated | not extracted yet |
| Lin 2020 Clinical evaluation of ridge preservation and augmentation with buccal bone deficiency by Er:YAG laser-assisted bone regenerative therapy DOI:10.1016/j.jds.2020.05.030 | 2020 | this review only | not stated | not extracted yet |
| Malcangi 2023 Therapeutic and Adverse Effects of Lasers in Dentistry: A Systematic Review DOI:10.3390/photonics10060650 | 2023 | this review only | not stated | not extracted yet |
| Mizutani 2016 Lasers in minimally invasive periodontal and peri‐implant therapy DOI:10.1111/prd.12123 | 2016 | this review only | not stated | not extracted yet |
| Nguyen 2015 Adjunctive Non‐Surgical Therapy of Inflamed Periodontal Pockets During Maintenance Therapy Using Diode Laser: A Randomized Clinical Trial DOI:10.1902/jop.2015.150152 | 2015 | this review only | not stated | not extracted yet |
| Pandarathodiyil 2020 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Sharaschandra 2022 Prehospital lung ultrasound in the distinction between pulmonary edema and exacerbation of chronic obstructive pulmonary disease. PMID:20223411 | 2010 | this review only | not stated | not extracted yet |
| Slot 2009 The Effect of a Pulsed Nd:YAG Laser in Non‐Surgical Periodontal Therapy DOI:10.1902/jop.2009.080571 | 2009 | this review only | not stated | not extracted yet |
| Taniguchi 2016 A Novel Surgical Procedure for Er:YAG Laser–Assisted Periodontal Regenerative Therapy: Case Series DOI:10.11607/prd.2515 | 2016 | this review only | not stated | not extracted yet |
| Werner 2024 Probing pocket depth reduction after non‐surgical periodontal therapy: Tooth‐related factors DOI:10.1002/jper.23-0285 | 2023 | this review only | not stated | not extracted yet |
| Zengin Celik 2019 Clinical and Microbiological Effects of the Use of Erbium: Yttrium–Aluminum–Garnet Laser on Chronic Periodontitis in Addition to… DOI:10.1089/photob.2018.4510 | 2019 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Laser-Assisted Strategies for Alveolar Bone Preservation After Tooth Extraction: A Systematic Review and Meta-Analysis. (2026) | 1 | 0.02 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients with chronic or generalized periodontitis | Periodontitis patients (Er:YAG pooled analysis: CAL gain in 4 to 6 mm pockets) |
| Intervention | Laser-assisted periodontal therapy (Er:YAG, Er,Cr:YSGG, Nd:YAG, diode, photodynamic therapy) | Er:YAG, diode, Nd:YAG, Er,Cr:YSGG, combination and photodynamic laser therapy as SRP adjuncts (n=26 studies, many narrative or review articles) |
| Comparison | Conventional SRP alone or placebo laser treatment | SRP alone |
| Outcomes | Probing depth and/or clinical attachment level (mean and SD), minimum follow-up 3 months | CAL gain (pooled for Er:YAG, 0 to 6 months); PD and microbial outcomes narrative |
| Study designs | RCTs or prospective clinical studies | RCTs, prospective studies and reviews listed in Table 1 (n=26) |
| Timing | Studies published January 2015 to October 2025; follow-up at least 3 months | Follow-up 3 to 6 months (mostly 6 months or less) |