Non-Cochrane · intervention · PM41868440
Effectiveness of Different Acceleration Methods for the En Masse Retraction of Upper Anterior Teeth: A Systematic Review and Meta-Analysis.
Mousa Mudar Mohammad, Hajeer Mohammad Y, Othman Mohamad J, et al. · Cureus · 2026 · PubMed · doi:10.7759/cureus.105562
Findings
Population Healthy orthodontic patients aged 16-35 years needing first premolar extraction for en masse retraction of the six upper anterior teeth
2 findings
| Flapless corticotomy (piezocision) during en masse retraction | Conventional en masse retraction without acceleration | Rate of en masse retraction (mm/month) Until end of retraction or follow-up of about 4 months · Orthodontic clinics | MD 0.24 [0.15, 0.34] Moderate Downgraded: inconsistency 2 studies · 65 participants |
| Corticoalveolar perforations (micro-osteoperforations) during en masse retraction | Conventional en masse retraction without acceleration | Rate of en masse retraction (mm/month) Until end of retraction or follow-up of about 4 months · Orthodontic clinics | MD 0.28 [0.19, 0.37] Low Downgraded: risk of bias, inconsistency 2 studies · 75 participants |
Included primary studies 9
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Hatrom 2020 Effect of piezocision corticotomy on en-masse retraction. PMID:33378476 | 2020 | 2 other reviews | Rate of en masse retraction (mm/month) | not extracted yet |
| Kumar 2024 Effect of micro-osteoperforations (MOPs) on the rate of en masse orthodontic tooth retraction : A randomized controlled trial. PMID:36018346 | 2024 | 2 other reviews | Rate of en masse retraction (mm/month) | not extracted yet |
| Al-Bozaie 2024 An Evaluation of the Rate and Type of Orthodontic Tooth Movement When Injecting Platelet-Rich Plasma During Mini-Implant-Based Segmented… PMID:38882220 | 2024 | 1 other review | not stated | not extracted yet |
| Chandak 2022 Effect of platelet-rich plasma on the rate of orthodontic tooth movement. PMID:35473999 | 2022 | 1 other review | not stated | not extracted yet |
| Raghav 2021 Effect of micro-osteoperforations on rate of space closure by mini-implant supported maxillary anterior en-masse retraction: A randomized… PMID:33598396 | 2021 | 1 other review | Rate of en masse retraction (mm/month) | not extracted yet |
| Khlef 2020 The effectiveness of traditional corticotomy vs flapless corticotomy in miniscrew-supported en-masse retraction of maxillary anterior… PMID:33158633 | 2020 | this review only | not stated | not extracted yet |
| Khlef 2022 Is It Possible to Achieve Favorable Accelerated Dental Changes with No Periodontal Complications When Retracting Upper Anterior Teeth… PMID:35295761 | 2022 | this review only | not stated | not extracted yet |
| Mousa 2025 Evaluation of low-level laser therapy and piezocision in the en-masse retraction of upper anterior teeth. PMID:40353446 | 2025 | this review only | Rate of en masse retraction (mm/month) | not extracted yet |
| Shaadouh 2024 Effectiveness of low-intensity electrical current in accelerating the en-masse retraction of the upper anterior teeth following… PMID:39316889 | 2024 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Healthy patients of both sexes aged 16-35 years requiring first premolar extraction for en masse retraction, complete dentition except third molars, no prior orthodontic treatment | Nine RCTs, 347 participants (mean age 21.6 years); Class II division 1 (n=6 trials) or Class I bimaxillary protrusion (n=3 trials) |
| Intervention | En masse retraction of the six anterior teeth assisted by surgical, physical, mechanical, biochemical, hormonal or pharmacological acceleration methods | Traditional corticotomy (n=2 trials), flapless corticotomy (n=4), corticoalveolar perforations (n=2), low-intensity electrical stimulation (n=1), platelet-rich plasma (n=2), flapless corticotomy plus low-level laser therapy (n=1) |
| Comparison | Another acceleration method or no acceleration | Conventional non-accelerated retraction (n=7 trials); traditional corticotomy vs flapless corticotomy (n=2) |
| Outcomes | Rate of tooth movement (mm/month) and overall treatment duration | Rate of en masse retraction in mm/month (all 9 trials); duration of retraction (1 trial) |
| Study designs | Randomized controlled trials published January 1995 to May 2025 | Nine parallel-group RCTs |
| Timing | Not specified | Follow-up until completion of retraction or 3-4 months |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | No | Partial Yes | no |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | Yes | Yes | yes |
| 8Included studies described in detail | Yes | Yes | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: Yes · NRSI: N/A | NRSI: N/A · RCT: Yes | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: No · NRSI: N/A | NRSI: N/A · RCT: No | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | No | No | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |