Non-Cochrane · intervention · PM41815628
Effects of Maxillary Sinus Augmentation on Endosseous Dental Implant Survival: A Systematic Review and Meta-Analysis.
Derbishi Ali A, Mubarki Ola, Hakami Razan M, et al. · Cureus · 2026 · PubMed · doi:10.7759/cureus.103201
Findings
Population Patients receiving dental implants in augmented maxillary sinuses
6 findings
| Maxillary sinus floor augmentation (MSFA) | None (single-arm pooled estimate) | Implant failure rate Follow-up 0.5 to 15 years (mean) · Meta-regression on mean follow-up duration (years) | Meta-regression slope 0.003 GRADE not reported 22 studies |
| Maxillary sinus floor augmentation (MSFA) | None (single-arm pooled estimate) | Marginal bone loss (mm) Not specified | Pooled mean 1.17 [0.59, 1.75] Low Downgraded: risk of bias, inconsistency 9 studies · 4502 participants |
| Maxillary sinus floor augmentation (MSFA) | None (single-arm pooled estimate) | Implant failure rate Follow-up 0.5 to 15 years (mean) | Pooled proportion 0.03 [0.02, 0.05] Low Downgraded: risk of bias, inconsistency 22 studies · 6860 participants |
| MSFA, lateral window (antrostomy) | None (single-arm pooled estimate) | Implant failure rate Follow-up 0.5 to 15 years (mean) · Surgical technique: Lateral window approach | Pooled proportion 0.04 [0.02, 0.06] GRADE not reported 11 studies · 3211 participants |
| MSFA, crestal (transalveolar, osteotome) | None (single-arm pooled estimate) | Implant failure rate Follow-up 0.5 to 15 years (mean) · Surgical technique: Crestal (osteotome) approach | Pooled proportion 0.00 [0.00, 0.09] GRADE not reported 2 studies · 96 participants |
| MSFA, mixed lateral and crestal | None (single-arm pooled estimate) | Implant failure rate Follow-up 0.5 to 15 years (mean) · Surgical technique: Mixed approach | Pooled proportion 0.04 [0.01, 0.08] GRADE not reported 9 studies · 3553 participants |
Included primary studies 40
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Hashem 2023 Redox potentials in hydro-organic media at normal and subzero temperatures. Ferro-ferricyanide and cytochrome c as models. PMID:202313 | 1978 | 1 other review | not stated | not extracted yet |
| Pichotano 2019 Evaluation of L-PRF combined with deproteinized bovine bone mineral for early implant placement after maxillary sinus augmentation: A… PMID:30690860 | 2019 | 1 other review | not stated | not extracted yet |
| Carmagnola 2024 Maxillary sinus lift augmentation: A randomized clinical trial with histological data comparing deproteinized bovine bone grafting vs… DOI:10.1111/cid.13359 | 2024 | this review only | not stated | not extracted yet |
| Carmagnola 2024 Maxillary sinus lift augmentation: A randomized clinical trial with histological data comparing deproteinized bovine bone grafting vs… PMID:38979855 | 2024 | this review only | not stated | not extracted yet |
| Erdem 2016 Three-Year Clinical and Radiographic Implant Follow-up in Sinus-Lifted Maxilla With Lateral Window Technique DOI:10.1097/id.0000000000000360 | 2016 | this review only | not stated | not extracted yet |
| Erdem 2016 Three-Year Clinical and Radiographic Implant Follow-up in Sinus-Lifted Maxilla With Lateral Window Technique. PMID:26579850 | 2016 | this review only | not stated | not extracted yet |
| Guljé 2014 Single crowns in the resorbed posterior maxilla supported by either 6-mm implants or by 11-mm implants combined with sinus floor elevation… PMID:25237669 | 2014 | this review only | not stated | not extracted yet |
| Ha 2020 Clinical outcome of implants placed in grafted maxillary sinus via lateral approach: A 10-year follow-up study DOI:10.1016/j.jds.2020.05.014 | 2020 | this review only | not stated | not extracted yet |
| Ha 2020 Clinical outcome of implants placed in grafted maxillary sinus via lateral approach: A 10-year follow-up study. PMID:32952884 | 2020 | this review only | not stated | not extracted yet |
| Hallman 2005 A 3-year prospective follow-up study of implant-supported fixed prostheses in patients subjected to maxillary sinus floor augmentation… DOI:10.1016/j.ijom.2004.09.009 | 2005 | this review only | not stated | not extracted yet |
| Hallman 2005 A 3-year prospective follow-up study of implant-supported fixed prostheses in patients subjected to maxillary sinus floor augmentation… PMID:15741036 | 2005 | this review only | not stated | not extracted yet |
| Hao 2021 [The relationships between different surgical approaches for maxillary sinus augmentation and implant failure and complications: a… PMID:34109366 | 2021 | this review only | not stated | not extracted yet |
| Jamcoski 2023 15‐Year Retrospective Study on the Success Rate of Maxillary Sinus Augmentation and Implants: Influence of Bone Substitute Type,… DOI:10.1155/2023/9144661 | 2023 | this review only | not stated | not extracted yet |
| Jamcoski 2023 15-Year Retrospective Study on the Success Rate of Maxillary Sinus Augmentation and Implants: Influence of Bone Substitute Type,… PMID:36860810 | 2023 | this review only | not stated | not extracted yet |
| Jue 2025 Maxillary Sinus Floor Augmentation With Autogenous Bone Versus Bovine Bone Mineral Mixed With 25% Autogenous Bone: A 1‐Year Multicenter,… DOI:10.1111/clr.14431 | 2025 | this review only | not stated | not extracted yet |
| Jue 2025 Maxillary Sinus Floor Augmentation With Autogenous Bone Versus Bovine Bone Mineral Mixed With 25% Autogenous Bone: A 1-Year Multicenter,… PMID:40095360 | 2025 | this review only | not stated | not extracted yet |
| Jurisic 2008 Maxillary sinus floor augmentation: comparing osteotome with lateral window immediate and delayed implant placements. An interim report DOI:10.1016/j.tripleo.2008.04.025 | 2008 | this review only | not stated | not extracted yet |
| Jurisic 2008 Maxillary sinus floor augmentation: comparing osteotome with lateral window immediate and delayed implant placements. An interim report. PMID:18602304 | 2008 | this review only | not stated | not extracted yet |
| Khouly 2017 Long-Term Implant Survival After 100 Maxillary Sinus Augmentations Using Plasma Rich in Growth Factors DOI:10.1097/id.0000000000000561 | 2017 | this review only | not stated | not extracted yet |
| Khouly 2017 Long-Term Implant Survival After 100 Maxillary Sinus Augmentations Using Plasma Rich in Growth Factors. PMID:28207599 | 2017 | this review only | not stated | not extracted yet |
| Kim HJ 2020 A retrospective study of implants placed following 1‐stage or 2‐stage maxillary sinus floor augmentation by the lateral window technique… DOI:10.1002/jper.19-0066 | 2019 | this review only | not stated | not extracted yet |
| Kim HJ 2020 A retrospective study of implants placed following 1-stage or 2-stage maxillary sinus floor augmentation by the lateral window technique… PMID:31372997 | 2020 | this review only | not stated | not extracted yet |
| Kim YK 2013 Relationship Between Prognosis of Dental Implants and Maxillary Sinusitis Associated with the Sinus Elevation Procedure DOI:10.11607/jomi.2739 | 2013 | this review only | not stated | not extracted yet |
| Kim YK 2013 Relationship between prognosis of dental implants and maxillary sinusitis associated with the sinus elevation procedure. PMID:23377064 | 2013 | this review only | not stated | not extracted yet |
| Krennmair 2019 Implant health and factors affecting peri‐implant marginal bone alteration for implants placed in staged maxillary sinus augmentation: A… DOI:10.1111/cid.12684 | 2019 | this review only | not stated | not extracted yet |
| Krennmair 2019 Implant health and factors affecting peri-implant marginal bone alteration for implants placed in staged maxillary sinus augmentation: A… PMID:30609163 | 2019 | this review only | not stated | not extracted yet |
| Lie 2021 Implant survival after graftless sinus floor augmentation in highly atrophic maxillae: a randomized controlled trial in a split mouth study DOI:10.1186/s40729-021-00387-y | 2021 | this review only | not stated | not extracted yet |
| Lie 2021 Implant survival after graftless sinus floor augmentation in highly atrophic maxillae: a randomized controlled trial in a split mouth study. PMID:34661774 | 2021 | this review only | not stated | not extracted yet |
| Liu 2019 Immediate implant placement combined with maxillary sinus floor elevation utilizing the transalveolar approach and nonsubmerged healing… DOI:10.1111/cid.12783 | 2019 | this review only | not stated | not extracted yet |
| Liu 2019 Immediate implant placement combined with maxillary sinus floor elevation utilizing the transalveolar approach and nonsubmerged healing… PMID:31044510 | 2019 | this review only | not stated | not extracted yet |
| Olson 2000 Long‐Term Assessment (5 to 71 Months) of Endosseous Dental Implants Placed in the Augmented Maxillary Sinus DOI:10.1902/annals.2000.5.1.152 | 2000 | this review only | not stated | not extracted yet |
| Olson 2000 Long-term assessment (5 to 71 months) of endosseous dental implants placed in the augmented maxillary sinus. PMID:11885175 | 2000 | this review only | not stated | not extracted yet |
| Pichotano 2019 Evaluation of L‐PRF combined with deproteinized bovine bone mineral for early implant placement after maxillary sinus augmentation: A… DOI:10.1111/cid.12713 | 2019 | this review only | not stated | not extracted yet |
| Sağlanmak 2025 Dental Implant Rehabilitation of Posterior Maxillary Edentulism via Sinus Augmentation Using the Lateral Window Technique: A Retrospective… PMID:39997599 | 2025 | this review only | not stated | not extracted yet |
| Tetsch 2010 Long‐term results after lateral and osteotome technique sinus floor elevation: a retrospective analysis of 2190 implants over a time… DOI:10.1111/j.1600-0501.2008.01661.x | 2010 | this review only | not stated | not extracted yet |
| Tetsch 2010 Long-term results after lateral and osteotome technique sinus floor elevation: a retrospective analysis of 2190 implants over a time… PMID:20443802 | 2010 | this review only | not stated | not extracted yet |
| Uckan 2011 Survival Rates of Implants Inserted in the Maxillary Sinus Area by Internal or External Approach DOI:10.1097/id.0b013e3182386d34 | 2011 | this review only | not stated | not extracted yet |
| Uckan 2011 Survival rates of implants inserted in the maxillary sinus area by internal or external approach. PMID:22051745 | 2011 | this review only | not stated | not extracted yet |
| Zhang 2024 Clinical outcomes and risk factor analysis of dental implants inserted with lateral maxillary sinus floor augmentation: A 3‐ to 8‐year… DOI:10.1111/jcpe.13947 | 2024 | this review only | not stated | not extracted yet |
| Zhang 2024 Clinical outcomes and risk factor analysis of dental implants inserted with lateral maxillary sinus floor augmentation: A 3- to 8-year… PMID:38246602 | 2024 | this review only | not stated | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients with endosseous dental implants placed in augmented maxillary sinuses; studies of zygomatic or pterygoid implants excluded | Patients with implants in augmented maxillary sinuses (6,860 implants, n=22 studies) |
| Intervention | Maxillary sinus floor augmentation (lateral window, crestal/osteotome, mixed approaches; graft materials) | Lateral window (n=11), crestal (n=2) and mixed (n=9) approaches per Figure 6 |
| Comparison | Lateral window versus crestal approach; graft type | No comparator (single-arm pooled proportions); subgroup comparison of surgical techniques |
| Outcomes | Implant failure rate (primary); marginal bone loss (secondary) | Implant failure rate (n=22); marginal bone loss (n=9) |
| Study designs | RCTs and prospective or retrospective cohort studies | 7 RCTs and 15 cohort studies (1 prospective, 14 retrospective) |
| Timing | Minimum follow-up of one year post-loading | Mean follow-up 0.5 to 15 years |
AMSTAR 2 items
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Partial Yes | no |
| 2Protocol established before the reviewcritical | Partial Yes | Partial Yes | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | No | No | yes |
| 8Included studies described in detail | No | Partial Yes | no |
| 9Risk of bias assessed satisfactorilycritical | RCT: Yes · NRSI: Yes | NRSI: Yes · RCT: Yes | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: Yes · NRSI: No | NRSI: No · RCT: Yes | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | Yes | Yes | yes |
| 14Heterogeneity explained | Yes | Yes | yes |
| 15Publication bias investigatedcritical | Yes | Yes | yes |
| 16Conflicts of interest reported | Yes | Yes | yes |
| Overall | Critically Low | Critically Low | yes |