Non-Cochrane · intervention · PM41658653
Comparative Evaluation of Pain Perception Between Needleless Jet Infiltration Anaesthesia and Conventional Needle Anaesthesia for Maxillary Primary Molars in Children: A Systematic Review and Meta-Analysis.
Kadam Utkarsha, Kalaskar Ritesh, Kalaskar Ashita R, et al. · Cureus · 2026 · PubMed · doi:10.7759/cureus.100909
Findings
Population Children aged 3-12 years undergoing dental procedures on maxillary primary molars
2 findings
| Needleless jet infiltration anaesthesia (INJEX) | Conventional needle infiltration anaesthesia | Pain during injection During injection | SMD 0.12 [-0.37, 0.60] Very low Downgraded: risk of bias, imprecision, inconsistency 2 studies · 244 participants |
| Needleless jet infiltration anaesthesia (INJEX) | Conventional needle infiltration anaesthesia | Pain during/after treatment During and after treatment | SMD 0.11 [-0.14, 0.36] Low Downgraded: risk of bias, imprecision 2 studies · 244 participants |
Included primary studies 6
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Altan 2021 Comparative evaluation of pain perception with a new needle-free system and dental needle method in children: a randomized clinical trial. PMID:34852779 | 2021 | this review only | not stated | not extracted yet |
| Belevcikli 2023 Effect of the new needle-free injection system on pain perception and dental anxiety during anesthesia: randomized controlled split-mouth… PMID:36819599 | 2023 | this review only | Pain during injection; Pain during/after treatment | not extracted yet |
| El-Dien Mohamed 2023 matched by author and year (probable) | NR | this review only | Pain during injection; Pain during/after treatment | not extracted yet |
| Elbadry 2023 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Ellatif 2018 matched by author and year (probable) | NR | this review only | not stated | not extracted yet |
| Oliveira 2018 Assessment of anesthetic properties and pain during needleless jet injection anesthesia: a randomized clinical trial. PMID:30673030 | 2019 | this review only | not stated | not extracted yet |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Children aged 3-12 years undergoing dental procedures involving maxillary primary molars | Children undergoing treatment of maxillary primary molars (n=6 studies; one study in adults) |
| Intervention | Needleless jet infiltration anaesthesia using the INJEX system | Needleless jet injection (INJEX or Comfort-In) (n=6) |
| Comparison | Conventional needle infiltration anaesthesia | Conventional needle infiltration (n=6) |
| Outcomes | Pain perception assessed by validated measures (VAS, Wong-Baker Faces, FLACC, FPS-R) | Pain during injection (n=2); pain during/after treatment (n=2) |
| Study designs | RCTs, parallel or split-mouth, English language | RCTs (n=6) |
| Timing | Not specified | During injection; during/after treatment |