Non-Cochrane · intervention · PM41602568

Effect of minimal intervention on carious lesions in primary teeth. An Umbrella review.

Padilla-Cáceres Tania Carola, Arbildo-Vega Heber Isac, Mamani-Cori Vilma, et al. · Frontiers in dental medicine · 2025 · PubMed · doi:10.3389/fdmed.2025.1751752

Findings

Population Children with carious lesions in primary teeth

51 findings

Atraumatic restorative treatment (ART)Not applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
Annual · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: van 't Hof et al. 2006 (SM3 ref 49); multiple-surface ART restorations with high-viscosity glass ionomer
Mean annual failure rate (%) 17
GRADE not reported
28 studies
Atraumatic restorative treatment (ART)Not applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
After 3 years · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: van 't Hof et al. 2006 (SM3 ref 49); single-surface ART restorations with high-viscosity glass ionomer
Pooled survival rate (%) 86
GRADE not reported
28 studies
Atraumatic restorative treatment (ART)Not applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
First 2 years · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: de Amorim et al. 2012 (SM3 ref 47); multiple-surface ART restorations
Pooled survival rate (%) 62 [51, 73]
GRADE not reported
27 studies
Atraumatic restorative treatment (ART)Not applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
After 1 year · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: van 't Hof et al. 2006 (SM3 ref 49); single-surface ART restorations with high-viscosity glass ionomer
Pooled survival rate (%) 95
GRADE not reported
28 studies
Atraumatic restorative treatment (ART)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Dorri et al. 2017 (SM3 ref 30); overall
OR 1.6 [1.13, 2.27]
GRADE not reported
13 studies
Atraumatic restorative treatment (ART)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2018 (SM3 ref 28); occlusal lesions
RR 1.01 [0.99, 1.03]
GRADE not reported
Studies not reported
Atraumatic restorative treatment (ART)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2017 (SM3 ref 34); overall
OR 0.89 [0.57, 1.37]
GRADE not reported
4 studies
Atraumatic restorative treatment (ART)Not applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
Annual · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: van 't Hof et al. 2006 (SM3 ref 49); single-surface ART restorations with high-viscosity glass ionomer
Mean annual failure rate (%) 4.7
GRADE not reported
28 studies
Atraumatic restorative treatment (ART)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2018 (SM3 ref 28); occlusoproximal lesions
RR 0.98 [0.94, 1.04]
GRADE not reported
Studies not reported
Atraumatic restorative treatment (ART)Not applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
First 2 years · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: de Amorim et al. 2012 (SM3 ref 47); single-surface ART restorations
Pooled survival rate (%) 93 [91, 94]
GRADE not reported
27 studies
Atraumatic restorative treatment (ART)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Raggio et al. 2013 (SM3 ref 44); overall
OR 1.18 [0.93, 1.49]
GRADE not reported
3 studies
Chemical-mechanical caries removalConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Deng et al. 2018 (SM3 ref 27); overall
MD 0.57 [0.04, 1.09]
GRADE not reported
10 studies
Chemical-mechanical caries removalConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Lai et al. 2015 (SM3 ref 41); overall
OR 0.33 [0.01, 8.22]
GRADE not reported
7 studies
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Bukhari et al. 2025 (SM3 ref 5); overall (OR)
OR 4.12 [3.12, 5.44]
GRADE not reported
Studies not reported
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Trieu et al. 2019 (SM3 ref 24); overall
OR 2.99 [2.03, 4.42]
GRADE not reported
6 studies
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Chibinski et al. 2017 (SM3 ref 33); overall
RR 2.54 [1.67, 3.85]
GRADE not reported
4 studies
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Oliveira et al. 2019 (SM3 ref 22); overall
WMD -1.15 [-1.48, -0.82]
GRADE not reported
2 studies
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Bukhari et al. 2025 (SM3 ref 5); overall (MD)
MD -0.27 [-0.46, -0.07]
GRADE not reported
Studies not reported
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Gao et al. 2016 (SM3 ref 37); overall
OR 0.81 [0.68, 0.89]
GRADE not reported
8 studies
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Alqalaleef et al. 2024 (SM3 ref 8); overall
OR 18.1 [3.89, 84.15]
GRADE not reported
12 studies
Silver diamine fluoride (SDF)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2018 (SM3 ref 28); occlusal lesions
RR 1.11 [1.03, 1.2]
GRADE not reported
Studies not reported
Fluoride varnishConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2022 (SM3 ref 13); proximal lesions
OR 2.1 [0.52, 9.0]
GRADE not reported
Studies not reported
Fluoride varnishConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2022 (SM3 ref 13); occlusal lesions
OR 1.1 [0.19, 6.0]
GRADE not reported
Studies not reported
Fluoride varnishConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2022 (SM3 ref 13); buccal/lingual lesions
OR 0.99 [0.1, 10.0]
GRADE not reported
Studies not reported
Fluoride varnishConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Marinho et al. 2013 (SM3 ref 45); overall
RR 0.81 [0.62, 1.06]
GRADE not reported
21 studies
Hall techniqueConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Schwendicke et al. 2021 (SM3 ref 16); overall
OR 8.35 [3.73, 18.68]
GRADE not reported
Studies not reported
Hall techniqueConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Hu et al. 2022 (SM3 ref 15); overall
RR 1.49 [1.15, 1.93]
GRADE not reported
5 studies
Hall techniqueConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Innes et al. 2015 (SM3 ref 38); overall
RR 0.18 [0.06, 0.56]
GRADE not reported
3 studies
Hall techniqueConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Chua et al. 2023 (SM3 ref 10); overall
OR 1.06 [0.65, 1.73]
GRADE not reported
4 studies
Hall techniqueConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2018 (SM3 ref 28); occlusoproximal lesions
RR 1.3 [1.09, 1.54]
GRADE not reported
Studies not reported
Selective caries excavation (partial or incomplete caries removal)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Aïem et al. 2020 (SM3 ref 20); overall
OR 0.1 [0.04, 0.25]
GRADE not reported
8 studies
Selective caries excavation (partial or incomplete caries removal)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Pedrotti et al. 2019 (SM3 ref 25); overall
OR 1.74 [1.01, 3.0]
GRADE not reported
4 studies
Selective caries excavation (partial or incomplete caries removal)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Schwendicke et al. 2021 (SM3 ref 16); overall
OR 4.43 [1.04, 18.77]
GRADE not reported
Studies not reported
Selective caries excavation (partial or incomplete caries removal)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Ricketts et al. 2013 (SM3 ref 43); overall
RR 0.33 [0.01, 7.62]
GRADE not reported
8 studies
Selective caries excavation (partial or incomplete caries removal)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Li et al. 2018 (SM3 ref 26); overall
OR 1.4 [0.69, 2.84]
GRADE not reported
7 studies
Selective caries excavation (partial or incomplete caries removal)Conventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Schwendicke et al. 2013 (SM3 ref 42); overall
OR 0.97 [0.64, 1.46]
GRADE not reported
10 studies
Laser-assisted caries treatmentConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Pagano et al. 2020 (SM3 ref 19); overall
RR 0.3 [0.11, 0.78]
GRADE not reported
Studies not reported
Laser-assisted caries treatmentConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Montedori et al. 2016 (SM3 ref 35); overall
RR 1.0 [0.99, 1.01]
GRADE not reported
9 studies
Resin infiltrationConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Dorri et al. 2015 (SM3 ref 40); proximal lesions
OR 0.15 [0.06, 0.39]
GRADE not reported
Studies not reported
Resin infiltrationConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Cebula et al. 2023 (SM3 ref 11); overall
OR 0.41 [0.29, 0.57]
GRADE not reported
11 studies
Resin infiltrationConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Chen et al. 2021 (SM3 ref 17); overall
OR 0.21 [0.15, 0.3]
GRADE not reported
Studies not reported
Resin infiltrationConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tedesco et al. 2022 (SM3 ref 13); proximal lesions
OR 6.9 [2.0, 24.0]
GRADE not reported
Studies not reported
Resin infiltrationConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Elrashid et al. 2019 (SM3 ref 23); overall
RR 0.48 [0.3, 0.75]
GRADE not reported
5 studies
SealantsConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Chen et al. 2021 (SM3 ref 17); overall
OR 0.23 [0.18, 0.3]
GRADE not reported
Studies not reported
SealantsConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Dorri et al. 2015 (SM3 ref 40); proximal lesions
OR 0.26 [0.13, 0.53]
GRADE not reported
Studies not reported
SealantsNot applicable (pooled single-arm survival or incidence)Restoration survival or incidence (pooled proportion)
First 3 years · Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: de Amorim et al. 2012 (SM3 ref 47); ART sealants in pits and fissures
Mean annual dentine lesion incidence rate (%) 1
GRADE not reported
27 studies
SealantsConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Schwendicke et al. 2021 (SM3 ref 16); overall
OR 5.0 [0.51, 49.27]
GRADE not reported
Studies not reported
SealantsConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Pagano et al. 2020 (SM3 ref 19); overall
RR 0.67 [0.35, 1.26]
GRADE not reported
Studies not reported
SealantsConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Ramamurthy et al. 2022 (SM3 ref 12); overall
OR 0.76 [0.41, 1.42]
GRADE not reported
5 studies
SealantsConventional treatment, non-invasive management, placebo or no treatment, as defined in each source systematic reviewEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Papageorgiou et al. 2017 (SM3 ref 32); overall
RR 1.06 [0.45, 2.49]
GRADE not reported
16 studies
Microinvasive techniques (resin infiltration and sealants)Non-invasive interventionsEfficacy outcome as defined in each source systematic review (caries arrest or progression, restoration survival or failure, pulp exposure)
Pediatric dental care (clinical and community settings, as defined in the source SR) · Source SR: Tasleem et al. 2025 (SM3 ref 4); overall
OR 0.31 [0.18, 0.51]
GRADE not reported
13 studies

Included primary studies 49

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Duangthip 2016
matched by author and year (probable)
NR1 other reviewnot statednot extracted yet
Aïem 2020
Caries removal strategies for deep carious lesions in primary teeth: Systematic review
DOI:10.1111/ipd.12616
2020this review onlynot statednot extracted yet
Alqalaleef 2024
The role of silver diamine fluoride as dental caries preventive and arresting agent: a systematic review and meta-analysis
DOI:10.3389/froh.2024.1492762
2024this review onlynot statednot extracted yet
Bukhari 2025
EFFECTIVENESS OF TOPICAL SILVER DIAMINE FLUORIDE FOR MANAGEMENT OF DENTAL CARIES IN CHILDREN AND EARLY ADOLESCENTS: A SYSTEMATIC REVIEW…
DOI:10.62610/rjor.2025.2.17.89
2025this review onlynot statednot extracted yet
Cebula 2023
Resin Infiltration of Non-Cavitated Proximal Caries Lesions in Primary and Permanent Teeth: A Systematic Review and Scenario Analysis of…
DOI:10.3390/jcm12020727
2023this review onlynot statednot extracted yet
Chaudhari 2022
A systematic review of randomized controlled trials on survival rate of atraumatic restorative treatment compared with conventional…
DOI:10.4103/jisppd.jisppd_119_22
2022this review onlynot statednot extracted yet
Chen 2021
Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis
DOI:10.1186/s12903-020-01364-4
2021this review onlynot statednot extracted yet
Chibinski 2017
Silver Diamine Fluoride Has Efficacy in Controlling Caries Progression in Primary Teeth: A Systematic Review and Meta-Analysis
DOI:10.1159/000478668
2017this review onlynot statednot extracted yet
Chua 2023
Outcomes of preformed metal crowns placed with the conventional and Hall techniques: A systematic review and meta‐analysis
DOI:10.1111/ipd.13029
2022this review onlynot statednot extracted yet
Contreras 2017
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
de Amorim 2012
Survival of atraumatic restorative treatment (ART) sealants and restorations: a meta-analysis
DOI:10.1007/s00784-011-0513-3
2011this review onlynot statednot extracted yet
Deng 2018
Effects of Papacarie on children with dental caries in primary teeth: a systematic review and meta‐analysis
DOI:10.1111/ipd.12364
2018this review onlynot statednot extracted yet
Dipalma 2025
Effectiveness of Dental Restorative Materials in the Atraumatic Treatment of Carious Primary Teeth in Pediatric Dentistry: A Systematic…
DOI:10.3390/children12040511
2025this review onlynot statednot extracted yet
Dorri 2015
Micro-invasive interventions for managing proximal dental decay in primary and permanent teeth
DOI:10.1002/14651858.cd010431.pub2
2015this review onlynot statednot extracted yet
Dorri 2017
Atraumatic restorative treatment versus conventional restorative treatment for managing dental caries
DOI:10.1002/14651858.cd008072.pub2
2017this review onlynot statednot extracted yet
Duangthip 2015
Non-surgical treatment of dentin caries in preschool children – systematic review
DOI:10.1186/s12903-015-0033-7
2015this review onlynot statednot extracted yet
Elrashid 2019
Efficacy of Resin Infiltrate in Noncavitated Proximal Carious Lesions: A Systematic Review and Meta-Analysis.
PMID:31198691
2019this review onlynot statednot extracted yet
Ferreira 2012
matched by author and year (probable)
NRthis review onlynot statednot extracted yet
Gao 2016
Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children
DOI:10.1177/2380084416661474
2016this review onlynot statednot extracted yet
Hu 2022
Hall technique for primary teeth: A systematic review and meta-analysis
DOI:10.1016/j.jdsr.2022.09.003
2022this review onlynot statednot extracted yet
Inchingolo 2024
Caries in Primary Molars: Is Silver Diamine Fluoride Effective in Prevention and Treatment? A Systematic Review
DOI:10.3390/app14052055
2024this review onlynot statednot extracted yet
Inchingolo 2025
Pre-formed crowns and pediatric dentistry: a systematic review of different techniques of restorations
DOI:10.22514/jocpd.2025.001
2025this review onlynot statednot extracted yet
Innes 2015
Preformed crowns for decayed primary molar teeth
DOI:10.1002/14651858.cd005512.pub3
2015this review onlynot statednot extracted yet
Jabin 2020
Effect of 38% silver diamine fluoride on control of dental caries in primary dentition: A Systematic review.
PMID:32509608
2020this review onlynot statednot extracted yet
Lai 2015
Comparison of Carisolv system vs traditional rotating instruments for caries removal in the primary dentition: A systematic review and…
DOI:10.3109/00016357.2015.1023353
2015this review onlynot statednot extracted yet
Li 2018
Selective versus non-selective removal for dental caries: a systematic review and meta-analysis
DOI:10.1080/00016357.2017.1392602
2017this review onlynot statednot extracted yet
Marinho 2013
Fluoride varnishes for preventing dental caries in children and adolescents
DOI:10.1002/14651858.cd002279.pub2
2013this review onlynot statednot extracted yet
Mohapatra 2025
Clinical Outcome Success of Silver-Modified Atraumatic Restorative Treatment (SMART) in Treating Children with Dental Caries in Primary…
DOI:10.1055/s-0044-1788659
2024this review onlynot statednot extracted yet
Montedori 2016
Lasers for caries removal in deciduous and permanent teeth
DOI:10.1002/14651858.cd010229.pub2
2016this review onlynot statednot extracted yet
Muntean 2024
Silver Diamine Fluoride in Pediatric Dentistry: Effectiveness in Preventing and Arresting Dental Caries—A Systematic Review
DOI:10.3390/children11040499
2024this review onlynot statednot extracted yet
Oliveira 2019
The Effect of Silver Diamine Fluoride in Preventing Caries in the Primary Dentition: A Systematic Review and Meta-Analysis
DOI:10.1159/000488686
2018this review onlynot statednot extracted yet
Pagano 2020
Lasers to prevent dental caries: a systematic review
DOI:10.1136/bmjopen-2020-038638
2020this review onlynot statednot extracted yet
Papageorgiou 2017
Performance of pit and fissure sealants according to tooth characteristics: A systematic review and meta-analysis
DOI:10.1016/j.jdent.2017.08.004
2017this review onlynot statednot extracted yet
Pedrotti 2019
Does selective carious tissue removal of soft dentin increase the restorative failure risk in primary teeth?
DOI:10.1016/j.adaj.2019.02.018
2019this review onlynot statednot extracted yet
Raggio 2013
Is Atraumatic restorative treatment an option for restoring occlusoproximal caries lesions in primary teeth? A systematic review and…
DOI:10.1111/ipd.12013
2012this review onlynot statednot extracted yet
Ramamurthy 2022
Sealants for preventing dental caries in primary teeth
DOI:10.1002/14651858.cd012981.pub2
2022this review onlynot statednot extracted yet
Ricketts 2006
Complete or ultraconservative removal of decayed tissue in unfilled teeth
DOI:10.1002/14651858.cd003808.pub2
2006this review onlynot statednot extracted yet
Ricketts 2013
Operative caries management in adults and children
DOI:10.1002/14651858.cd003808.pub3
2013this review onlynot statednot extracted yet
Ruengrungsom 2018
Comparison of ART and conventional techniques on clinical performance of glass-ionomer cement restorations in load bearing areas of…
DOI:10.1016/j.jdent.2018.07.008
2018this review onlynot statednot extracted yet
Santamaría 2020
How to Intervene in the Caries Process: Dentin Caries in Primary Teeth
DOI:10.1159/000508899
2020this review onlynot statednot extracted yet
Schwendicke 2013
Incomplete Caries Removal
DOI:10.1177/0022034513477425
2013this review onlynot statednot extracted yet
Schwendicke 2021
Interventions for treating cavitated or dentine carious lesions
DOI:10.1002/14651858.cd013039.pub2
2021this review onlynot statednot extracted yet
Tasleem 2025
Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and meta-analysis
DOI:10.1186/s12903-024-05400-5
2025this review onlynot statednot extracted yet
Tedesco 2017
<scp>ART</scp> is an alternative for restoring occlusoproximal cavities in primary teeth – evidence from an updated systematic review and…
DOI:10.1111/ipd.12252
2016this review onlynot statednot extracted yet
Tedesco 2018
Scientific evidence for the management of dentin caries lesions in pediatric dentistry: A systematic review and network meta-analysis
DOI:10.1371/journal.pone.0206296
2018this review onlynot statednot extracted yet
Tedesco 2022
Nonrestorative treatment of initial caries lesion in primary teeth: a systematic review and network meta-analysis
DOI:10.1080/00016357.2021.1928748
2021this review onlynot statednot extracted yet
Trieu 2019
Silver diamine fluoride versus sodium fluoride for arresting dentine caries in children: a systematic review and meta-analysis
DOI:10.1038/s41598-019-38569-9
2019this review onlynot statednot extracted yet
van 't Hof 2006
The Atraumatic Restorative Treatment (ART) approach for managing dental caries: a meta-analysis
DOI:10.1111/j.1875-595x.2006.tb00339.x
2006this review onlynot statednot extracted yet
Vishwanathaiah 2024
Effectiveness of silver diamine fluoride (SDF) in arresting coronal dental caries in children and adolescents: a systematic review
DOI:10.22514/jocpd.2024.101
2024this review onlynot statednot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationChildren with carious lesions in primary teethChildren with carious primary teeth (49 systematic reviews, 634 primary studies)
InterventionMinimally invasive strategies: SDF, ART, sealants, resin infiltration, fluoride varnish, Hall technique, chemical-mechanical caries removal, laser, selective caries excavationSDF (n=15 SRs), ART (n=10), selective excavation (n=9), Hall technique (n=6), resin infiltration (n=6), sealant (n=6), chemical-mechanical removal (n=3), fluoride varnish (n=2), laser (n=2)
ComparisonConventional restorative or operative treatment, non-invasive management, placebo or no treatment, as defined in the included reviewsConventional treatment, no treatment, placebo or other non-invasive management as defined in each review
OutcomesCaries arrest or progression, restoration survival or failure, pulp exposure or vitality, retreatment, absence of periapical pathologyCaries arrest, restoration survival and failure, pulp exposure (as reported by included reviews)
Study designsSystematic reviews with or without meta-analysisSystematic reviews with and without meta-analysis (n=49)
TimingNot specifiedNot specified