Non-Cochrane · prevalence · PM41594051

Over-Prescription of Antibiotics for Pulpitis: A Systematic Review and Meta-Analysis of Cross-Sectional Surveys.

Delgado-Giugni Vanessa, León-López María, Crespo-Gallardo Isabel, et al. · Antibiotics (Basel, Switzerland) · 2025 · PubMed · doi:10.3390/antibiotics15010013

Findings

4 findings

Population
Dentists (general dental practitioners and endodontists)Systemic antibiotic prescribing for pulpitisNot applicable (single-group prevalence)Proportion of dentists prescribing systemic antibiotics for pulpitis
Surveys published 2015 to 2024 · Sensitivity analysis excluding two high-prevalence studies
Pooled prevalence (%) 13.3 [8.0, 21.3]
GRADE not reported
10 studies
Dentists (general dental practitioners and endodontists)Systemic antibiotic prescribing for pulpitisNot applicable (single-group prevalence)Proportion of dentists prescribing systemic antibiotics for pulpitis
Surveys published 2015 to 2024
Pooled prevalence (%) 19.2 [10.4, 32.6]
Very low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
12 studies · 3189 participants
General dental practitionersSystemic antibiotic prescribing for pulpitisNot applicable (single-group prevalence)Proportion of dentists prescribing systemic antibiotics for pulpitis
Surveys published 2015 to 2024 · General dental practitioners
Pooled prevalence (%) 26.9 [14.9, 43.5]
GRADE not reported
10 studies · 2398 participants
EndodontistsSystemic antibiotic prescribing for pulpitisNot applicable (single-group prevalence)Proportion of dentists prescribing systemic antibiotics for pulpitis
Surveys published 2015 to 2024 · Endodontists
Pooled prevalence (%) 5.1 [1.2, 19.2]
GRADE not reported
3 studies · 791 participants

Included primary studies 12

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Ozmen 2024
Antibiotic use in pediatric dental infections: knowledge and awareness levels of dentists.
PMID:39438651
20242 other reviewsProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Alattas 2017
Prescription of antibiotics for pulpal and periapical pathology among dentists in southern Saudi Arabia.
PMID:28455077
2017this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Alonso-Ezpeleta 2018
Use of antibiotics by spanish dentists receiving postgraduate training in endodontics.
PMID:30057712
2018this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Babar 2022
An evaluation of antibiotic prescribing practices among dentists in Lahore: A cross-sectional study
DOI:10.54393/pjhs.v3i04.84
2022this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Bolfoni 2018
Antibiotic prescription for endodontic infections: a survey of Brazilian Endodontists.
PMID:28744872
2018this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Dias 2022
Antibiotic indication in endodontics by Colombian dentists with different levels of training: a survey.
PMID:36748738
2022this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Dominguez-Dominguez 2021
Antibiotics Prescription by Spanish General Practitioners in Primary Dental Care.
PMID:34208145
2021this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Drobac 2021
Antibiotic Prescribing Practices in Endodontic Infections: A Survey of Dentists in Serbia.
PMID:33445544
2021this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Iqbal 2015
The Attitudes of Dentists Towards the Prescription of Antibiotics During Endodontic Treatment in North of Saudi Arabia.
PMID:26155570
2015this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Maslamani 2018
Antibiotic and Analgesic Prescription Patterns among Dentists or Management of Dental Pain and Infection during Endodontic Treatment.
PMID:29262417
2018this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Mengari 2020
Coupling of rigid to flexible imaging multifibers.
PMID:20208616
1978this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet
Yaqoob 2024
Evaluation of dentists' clinical practices and antibiotic use in managing endodontic emergencies in Karachi, Pakistan: a cross-sectional…
PMID:39732678
2024this review onlyProportion of dentists prescribing systemic antibiotics for pulpitisnot extracted yet

Overlap with other reviews

Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.

Review question

ElementPlanned (methods)Found (results)
PopulationLicensed dentists (general practitioners and specialists)Dentists (n=3189): GDPs (n=2398), endodontists (n=791)
InterventionNot applicable (prevalence review; Condition: antibiotic prescribing)Not applicable
ComparisonNot applicableNot applicable
OutcomesProportion of dentists prescribing systemic antibiotics for pulpitisPooled prevalence of antibiotic prescribing for pulpitis (12 studies)
Study designsObservational studies (cross-sectional surveys); published from 201512 cross-sectional surveys (Saudi Arabia, Pakistan, Kuwait, Turkey, Spain, Serbia, Brazil, Colombia)
TimingNot specifiedStudies published 2015 to 2024