Non-Cochrane · prognostic · PM41587408
Impact of Open Proximal Contacts on Peri-Implant Diseases: A Systematic Review and Meta-Analysis.
Atieh Momen A, Shah Maanas, Hakam Abeer, et al. · Clinical and experimental dental research · 2026 · PubMed · doi:10.1002/cre2.70278
Findings
Population Adults (18 years or older) with implant-supported fixed prostheses in function for at least 1 year, adjacent to natural teeth or non-splinted implants
8 findings
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Changes in marginal bone levels (mm) University clinics and one private practice; implant level analysis · Leave-one-study-out: Ko et al. (2024) removed | MD 0.16 [-0.08, 0.39] GRADE not reported 3 studies |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Changes in probing pocket depths (mm) Follow-up 24 to 60 months · University clinics and one private practice; implant level analysis | MD 0.11 [-0.29, 0.51] 0.11 [-0.29, 0.51] mm Very low Downgraded: risk of bias, inconsistency 3 studies · 372 participants |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Changes in marginal bone levels (mm) Follow-up 24 to 84 months · University clinics and one private practice; implant level analysis | MD 0.07 [-0.09, 0.24] 0.07 [-0.09, 0.24] mm Very low Downgraded: risk of bias, inconsistency 4 studies · 4697 participants |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Changes in marginal bone levels (mm) University clinics and one private practice; implant level analysis · Leave-one-study-out: Latimer et al. (2021) removed | MD 0.03 [-0.08, 0.14] GRADE not reported 3 studies |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Changes in marginal bone levels (mm) University clinics and one private practice; implant level analysis · Leave-one-study-out: Byun et al. (2015) removed | MD 0.04 [-0.15, 0.24] GRADE not reported 3 studies |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Peri-implant mucositis Follow-up 60 months · University clinics and one private practice; implant level analysis | RR 1.74 [1.06, 2.86] 182 [15, 458] more per 1000 Low Downgraded: risk of bias, imprecision 1 study · 142 participants |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Changes in marginal bone levels (mm) University clinics and one private practice; implant level analysis · Leave-one-study-out: French et al. (2019) removed | MD 0.15 [-0.18, 0.48] GRADE not reported 3 studies |
| Open proximal contact adjacent to implant restoration | Closed proximal contact adjacent to implant restoration | Peri-implantitis Follow-up 60 to 84 months · University clinics and one private practice; implant level analysis | RR 1.63 [0.88, 3.02] 58 [-11, 186] more per 1000 Low Downgraded: risk of bias, inconsistency 2 studies · 328 participants |
Included primary studies 10
Open in Studies| Study | Year | Also included by | Outcomes it informs here | Trial data |
|---|---|---|---|---|
| Alhakeem 2023 Risk indicators of long-term outcome of implant therapy in patients with a history of severe periodontitis or no history of periodontitis:… PMID:35090086 | 2023 | 1 other review | Peri-implantitis | not extracted yet |
| Alhakeem 2023 Risk indicators of long‐term outcome of implant therapy in patients with a history of severe periodontitis or no history of periodontitis:… DOI:10.1111/idh.12587 | 2022 | this review only | Peri-implantitis | not extracted yet |
| Byun 2015 Analysis of proximal contact loss between implant‐supported fixed dental prostheses and adjacent teeth in relation to influential factors… DOI:10.1111/clr.12373 | 2014 | this review only | Changes in marginal bone levels (mm); Changes in probing pocket depths (mm) | not extracted yet |
| Byun 2015 Analysis of proximal contact loss between implant-supported fixed dental prostheses and adjacent teeth in relation to influential factors… PMID:24712313 | 2015 | this review only | Changes in marginal bone levels (mm); Changes in probing pocket depths (mm) | not extracted yet |
| French 2019 Interproximal contact loss in a retrospective cross-sectional study of 4325 implants: Distribution and incidence and the effect on bone… DOI:10.1016/j.prosdent.2018.11.011 | 2019 | this review only | Changes in marginal bone levels (mm) | not extracted yet |
| French 2019 Interproximal contact loss in a retrospective cross-sectional study of 4325 implants: Distribution and incidence and the effect on bone… PMID:30885585 | 2019 | this review only | Changes in marginal bone levels (mm) | not extracted yet |
| Ko 2024 A two-year prospective study to compare the peri-implant parameters of posterior implant-supported single crowns with and without mesial… DOI:10.1016/j.jds.2023.11.014 | 2024 | this review only | Changes in marginal bone levels (mm); Changes in probing pocket depths (mm) | not extracted yet |
| Ko 2024 A two-year prospective study to compare the peri-implant parameters of posterior implant-supported single crowns with and without mesial… PMID:39035261 | 2024 | this review only | Changes in marginal bone levels (mm); Changes in probing pocket depths (mm) | not extracted yet |
| Latimer 2021 Interproximal open contacts between implant restorations and adjacent natural teeth as a risk‐indicator for peri‐implant disease—A… DOI:10.1111/clr.13730 | 2021 | this review only | Changes in marginal bone levels (mm); Changes in probing pocket depths (mm); Peri-implant mucositis; Peri-implantitis | not extracted yet |
| Latimer 2021 Interproximal open contacts between implant restorations and adjacent natural teeth as a risk-indicator for peri-implant disease-A… PMID:33629375 | 2021 | this review only | Changes in marginal bone levels (mm); Changes in probing pocket depths (mm); Peri-implant mucositis; Peri-implantitis | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match). Only the non-Cochrane dental reviews have study lists, so overlap with Cochrane reviews is not counted yet.
| Review | Shared studies | Jaccard |
|---|---|---|
| Keratinized Mucosa Width and Incidence of Peri-Implant Diseases: A Systematic Review With Meta-Analysis. (2026) | 1 | 0.05 |
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Human adults aged 18 years or older with implant-supported fixed prostheses | Adults with implant-supported fixed prostheses (4883 implants; 1050 with open proximal contacts) |
| Intervention | Open proximal contacts between implant-supported fixed prostheses and natural tooth or two adjacent non-splinted implants | Open proximal contacts (n=1050 implants) |
| Comparison | Closed proximal contacts in the same situations | Closed proximal contacts |
| Outcomes | Changes in marginal bone level (primary); changes in probing pocket depth; incidence of peri-implant mucositis; incidence of peri-implantitis | Marginal bone level change (4 studies); probing pocket depth (3 studies); peri-implant mucositis (1 study); peri-implantitis (2 studies) |
| Study designs | Non-randomized observational studies | 5 non-randomized studies (cross-sectional, retrospective cohort, case-control) |
| Timing | Implant restorations in function for at least 1 year | Follow-up 24 to 84 months |