Non-Cochrane · intervention · PM41394781

Comparison of intraoperative blood loss in piezoelectric vs. conventional technique surgeries: a systematic review and meta-analysis.

Ahmadi Sina, Rajaei Sahar, Alimohammadi Farnoosh, et al. · Frontiers in oral health · 2025 · PubMed · doi:10.3389/froh.2025.1687571

Findings

Population Patients undergoing orthognathic surgery

13 findings

Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Procedure type: BSSO and Le Fort I combined
MD -103.21 [-123.61, -82.81]
GRADE not reported
3 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Sensitivity: leave-one-out, omitting Spinelli et al. 2014
MD -82.29 [-99.1, -65.49]
GRADE not reported
5 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Geographic location: Africa
MD -76.4 [-89.58, -63.22]
GRADE not reported
1 study
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Sensitivity: leave-one-out, omitting Sato et al. 2023
MD -78.0 [-92.43, -63.58]
GRADE not reported
5 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Sensitivity: leave-one-out, omitting Demirbas et al. 2015
MD -84.04 [-100.46, -67.62]
GRADE not reported
5 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Geographic location: Europe
MD -54.41 [-105.14, -3.67]
GRADE not reported
2 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Procedure type: Le Fort I only
MD -36.66 [-106.56, 33.24]
GRADE not reported
1 study
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery
MD -81.73 [-97.3, -66.16]
GRADE not reported
6 studies · 144 participants
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Geographic location: Asia
MD -91.12 [-118.2, -64.04]
GRADE not reported
3 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Sensitivity: leave-one-out, omitting Barakat et al. 2025
MD -84.58 [-107.48, -61.69]
GRADE not reported
5 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Procedure type: BSSO only
MD -73.39 [-82.98, -63.8]
GRADE not reported
2 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Sensitivity: leave-one-out, omitting Akbar et al. 2015
MD -74.71 [-83.89, -65.52]
GRADE not reported
5 studies
Piezosurgery (piezoelectric osteotomy)Conventional osteotomy instruments (saws, burs)Intraoperative blood loss (mL)
Intraoperative · Orthognathic surgery · Sensitivity: leave-one-out, omitting Pattabhi et al. 2024
MD -86.91 [-106.54, -67.29]
GRADE not reported
5 studies

Included primary studies 6

Open in Studies
StudyYearAlso included byOutcomes it informs hereTrial data
Akbar 2015
Critical Analysis of Piezoelectric Surgery with Oscillating Saw in Bimaxillary Orthognathic Surgery.
PMID:28689523
2017this review onlyIntraoperative blood loss (mL)not extracted yet
Barakat 2025
Piezosurgery Versus Conventional Saw in Mandibular Genioplasty: A Comparative study
DOI:10.21608/asdj.2025.352490.1787
2025this review onlyIntraoperative blood loss (mL)not extracted yet
Demirbas 2015
Is Ultrasonic Bone Scalpel Useful in Le Fort I Osteotomy?
PMID:31669455
2020this review onlyIntraoperative blood loss (mL)not extracted yet
Pattabhi 2024
matched by author and year (probable)
NRthis review onlyIntraoperative blood loss (mL)not extracted yet
Sato 2023
Advantages of a High-Powered Ultrasonic Vibration Cutting Device for Orthognathic Surgeries.
PMID:37943066
2024this review onlyIntraoperative blood loss (mL)not extracted yet
Spinelli 2014
Comparison of piezosurgery and traditional saw in bimaxillary orthognathic surgery.
PMID:24742747
2014this review onlyIntraoperative blood loss (mL)not extracted yet

Review question

ElementPlanned (methods)Found (results)
PopulationPatients who underwent orthognathic surgeryOrthognathic surgery patients (n=144 participants; 252 surgeries)
InterventionPiezoelectric osteotomyPiezosurgery (n=6 studies)
ComparisonConventional osteotomy (saws, burs, chisels)Conventional cutting techniques (saw, bur) (n=6 studies)
OutcomesIntraoperative blood lossIntraoperative blood loss in mL (n=6 studies)
Study designsObservational studies and controlled trials; English languageObservational (cohort) studies (n=6)
TimingNot specifiedIntraoperative