Cochrane · systematic review · CD012937
Routine monitoring of gastric residual for prevention of necrotising enterocolitis in preterm infants
Abiramalatha, T, Thanigainathan, S, Ramaswamy, VV, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
14
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 7.1%Low 9 · 64.3%Moderate 4 · 28.6%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings table ‐ routine monitoring vs. no routine monitoring of gastric residual in preterm infants
Population: preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Risk of necrotising enterocolitis stage ≥ 2 Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | RR 1.08 [0.46, 2.57] | 4 studies · 334 participants | Moderate Downgraded: imprecision |
Time to establish full enteral feeds (days) Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | no estimate extracted | 4 studies · 334 participants | Moderate Downgraded: imprecision |
Time to regain birth weight (days) Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | no estimate extracted | 1 study · 80 participants | Low Downgraded: imprecision |
Number of infants with feed interruption episodes (lasting ≥ 12 hours) Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | RR 2.21 [1.53, 3.2] | 3 studies · 191 participants | Low Downgraded: risk of bias |
Number of total parenteral nutrition days Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | no estimate extracted | 4 studies · 334 participants | Moderate Downgraded: imprecision |
Risk of invasive infection Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | RR 1.5 [1.02, 2.19] | 4 studies · 334 participants | Moderate Downgraded: imprecision |
All‐cause mortality before hospital discharge Summary of findings table ‐ routine monitoring vs no routine monitoring of gastric residual | RR 2.14 [0.77, 5.97] | 3 studies · 273 participants | Low Downgraded: imprecision |
Summary of findings table ‐ Quality and volume of gastric residual compared to quality of gastric residual alone for feed interruption in preterm infants
Population: feed interruption while monitoring gastric residual
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Risk of necrotising enterocolitis stage ≥ 2 Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | RR 5.35 [0.26, 108.27] | 1 study · 87 participants | Low Downgraded: imprecision |
Time to establish full enteral feeds Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | no estimate extracted | 1 study · 87 participants | Low Downgraded: imprecision |
Time to regain birth weight (days) Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | no estimate extracted | 1 study · 87 participants | Low Downgraded: imprecision |
Number of infants with feed interruption episodes (lasting ≥ 12 hours) Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | RR 3.21 [0.13, 76.67] | 1 study · 87 participants | Very low Downgraded: risk of bias, imprecision |
Number of total parenteral nutrition days Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | no estimate extracted | 1 study · 87 participants | Low Downgraded: imprecision |
Risk of invasive Infection Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | RR 5.35 [0.26, 108.27] | 1 study · 87 participants | Low Downgraded: imprecision |
All‐cause mortality before hospital discharge Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone | RR 3.21 [0.13, 76.67] | 1 study · 87 participants | Low Downgraded: imprecision |
Routine monitoring of gastric residuals compared to no routine monitoring of gastric residuals for prevention of necrotising enterocolitis in preterm infants
Population: prevention of necrotising enterocolitis in preterm infants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of infants with NEC stage 2 or 3 Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | RR 3.07 [0.5, 18.77] | 2 studies · 141 participants | Low Downgraded: imprecision |
Number of infants with episodes of interruption of feeds (lasting ≥ 12 hours) Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | RR 2.07 [1.39, 3.07] | 2 studies · 141 participants | Low Downgraded: risk of bias, imprecision |
Time to reach full enteral feeds (days) Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | no estimate extracted | 2 studies · 141 participants | Low Downgraded: risk of bias, imprecision |
Time to regain birth weight (days) Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | no estimate extracted | 1 study · 80 participants | Low Downgraded: risk of bias, imprecision |
Number of TPN days Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | no estimate extracted | 2 studies · 141 participants | Low Downgraded: risk of bias, imprecision |
Number of infants with extrauterine growth restriction at discharge Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | RR 0.89 [0.75, 1.05] | 1 study · 80 participants | Low Downgraded: risk of bias, imprecision |
All‐cause mortality before discharge Routine monitoring of gastric residuals vs no routine monitoring of gastric residuals | RR 1.25 [0.36, 4.32] | 1 study · 80 participants | Low Downgraded: risk of bias, imprecision |