Cochrane · systematic review · CD012868

Fludrocortisone for orthostatic hypotension

Veazie, S, Peterson, K, Ansari, Y, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 50%Very low 3 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Fludrocortisone compared to placebo for people with diabetes and orthostatic hypotension

Population: people with diabetes and orthostatic hypotension
6 questions
OutcomeEffectEvidenceStatus / GRADE
Blood pressure outcomes
Fludrocortisone vs placebo
no estimate extracted1 study · 6 participantsVery low
Downgraded: risk of bias, imprecision
Orthostatic symptoms
Fludrocortisone vs placebo
no estimate extracted1 study · 6 participantsVery low
Downgraded: risk of bias, imprecision
Frequency and severity of postural lightheadedness
Fludrocortisone vs placebo
no estimate extracted0 participantsUngraded
Frequency of syncope
Fludrocortisone vs placebo
no estimate extracted0 participantsUngraded
Quality of life
Fludrocortisone vs placebo
no estimate extracted0 participantsUngraded
Serious or severe adverse events
Fludrocortisone vs placebo
no estimate extracted1 study · 6 participantsVery low
Downgraded: risk of bias, imprecision