Cochrane · systematic review · CD012753
Xenon as an adjuvant to therapeutic hypothermia in near‐term and term newborns with hypoxic‐ischaemic encephalopathy
Rüegger, CM, Davis, PG, Cheong, JL · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
1
No studies
7
Included studies
NR
No studies 7 · 87.5%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: late preterm or term newborns with hypoxic‐ischaemic encephalopathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Death or major neurodevelopmental disability in infancy | no estimate extracted | NR | No studies |
Mortality at latest reported age | RR 1.22 [0.56, 2.67] | 1 study · 92 participants | Low |
Major neurodevelopmental disability in infancy | no estimate extracted | NR | No studies |
Major neurodevelopmental disability at school age | no estimate extracted | NR | No studies |
Cerebral palsy in infancy | no estimate extracted | NR | No studies |
Developmental delay or intellectual impairment in infancy | no estimate extracted | NR | No studies |
Blindness vision in infancy | no estimate extracted | NR | No studies |
Sensorineural deafness in infancy requiring amplification | no estimate extracted | NR | No studies |