Cochrane · systematic review · CD012455
Melatonin for the promotion of sleep in adults in the intensive care unit
Lewis, SR, Pritchard, MW, Schofield‐Robinson, OJ, et al. · Cochrane Database of Systematic Reviews · 2018 · Cochrane Library
Emergency and Critical CareAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: adult patients in the ICU
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Quantity and quality of sleep as measured through reports of participants or of family members or by personnel assessments Data collected at end of | no estimate extracted | 3 studies · 139 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Quantity and quality of sleep as measured by PSG, actigraphy, BIS, or EEG Data collected at end of | no estimate extracted | 2 studies · 37 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Anxiety or depression, or both Data collected at end of | no estimate extracted | 1 study · 82 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Mortality Study authors did not report final timepoint for data collection. | no estimate extracted | 2 studies · 94 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Length of stay in the ICU | no estimate extracted | 1 study · 82 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |
Adverse events (such as nausea, dizziness and headache) Data collected at end of | no estimate extracted | 2 studies · 107 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness |