Cochrane · systematic review · CD012375
Oxytocin antagonists for assisted reproduction
Craciunas, L, Tsampras, N, Kollmann, M, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Oxytocin antagonists compared to control for assisted reproduction
Population: women undergoing embryo transfer as part of assisted reproduction
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth Oxytocin antagonists vs control | RR 1.05 [0.88, 1.24] | 1 study · 800 participants | Low Downgraded: imprecision |
Miscarriage Oxytocin antagonists vs control | RR 1.08 [0.75, 1.56] | 5 studies · 1424 participants | Very low Downgraded: risk of bias, imprecision |
Clinical pregnancy Oxytocin antagonists vs control | RR 1.5 [1.18, 1.89] | 7 studies · 1646 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Complications Oxytocin antagonists vs control | no estimate extracted | 6 studies · 1464 participants | Very low Downgraded: risk of bias, imprecision |