Cochrane · systematic review · CD012277
Computerised cognitive training for 12 or more weeks for maintaining cognitive function in cognitively healthy people in late life
Gates, NJ, Rutjes, AWS, Di Nisio, M, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
10
No studies
5
Included studies
NR
No studies 5 · 33.3%Ungraded 0 · 0%Very low 3 · 20%Low 7 · 46.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyComparison
Population: cognitively healthy people in late life
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global cognitive function measured at the end of the intervention period (12 weeks) | no estimate extracted | 2 studies · 232 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: episodic memory measured at the end of the intervention period (12 to 17 weeks) | no estimate extracted | 4 studies · 439 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: speed of processing measured at the end of the intervention period (12 to 16 weeks) | no estimate extracted | 2 studies · 138 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: executive functioning measured at the end of the intervention period (12 to 17 weeks) | no estimate extracted | 3 studies · 230 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: working memory measured at the end of the intervention period (12 to 16 weeks) | no estimate extracted | 3 studies · 392 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life at the end of the intervention period | no estimate extracted | NR | No studies |
Number of participants experiencing 1 or more serious adverse events at the end of the intervention period | no estimate extracted | NR | No studies |
Comparison
Population: cognitively healthy people in late life
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global cognitive function measured at the end of the intervention period | no estimate extracted | NR | No studies |
Cognitive subdomain: episodic memory measured at the end of the intervention period (6 months) | no estimate extracted | 1 study · 150 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: speed of processing measured at the end of the intervention period (12 to 16 weeks) | no estimate extracted | 2 studies · 204 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: executive functioning measured at the end of the intervention period (12 weeks to 6 months) | no estimate extracted | 2 studies · 292 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: working memory measured at the end of the intervention period (16 weeks) | no estimate extracted | 1 study · 60 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: verbal fluency measured at the end of the intervention period (6 months) | no estimate extracted | 1 study · 150 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life at the end of the intervention period | no estimate extracted | NR | No studies |
Number of participants experiencing 1 or more serious adverse events at the end of the intervention period | no estimate extracted | NR | No studies |
Comparison
Population: cognitively healthy people in late life
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global cognitive function measured at the end of | no estimate extracted | 2 studies · 198 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: episodic memory measured at the end of | no estimate extracted | 4 studies · 439 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: speed of processing measured at the end of | no estimate extracted | 2 studies · 138 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: executive functioning measured at the end of | no estimate extracted | 3 studies · 230 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: working memory measured at the end of | no estimate extracted | 3 studies · 392 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life | no estimate extracted | NR | No studies |
Number of participants experiencing 1 or more serious adverse events | no estimate extracted | NR | No studies |
Comparison
Population: cognitively healthy people in late life
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Global cognitive function measured at the end of | no estimate extracted | NR | No studies |
Cognitive subdomain: episodic memory measured at the end of | no estimate extracted | 1 study · 150 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: speed of processing measured at the end of | no estimate extracted | 2 studies · 204 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: executive functioning measured at the end of | no estimate extracted | 2 studies · 292 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: working memory measured at the end of | no estimate extracted | 1 study · 60 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Cognitive subdomain: verbal fluency measured at the end of | no estimate extracted | 1 study · 150 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Quality of life | no estimate extracted | NR | No studies |
Number of participants experiencing 1 or more serious adverse events | no estimate extracted | NR | No studies |