Cochrane · systematic review · CD012188

Gabapentin for fibromyalgia pain in adults

Cooper, TE, Derry, S, Wiffen, PJ, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 6 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Gabapentin compared with placebo for fibromyalgia

Population: adults with fibromyalgia
6 questions
OutcomeEffectEvidenceStatus / GRADE
30% pain reduction at 12 weeks
Gabapentin vs placebo
no estimate extracted1 study · 150 participantsVery low
50% pain reduction at 12 weeks
Gabapentin vs placebo
no estimate extractedNRVery low
PGIC ‐ any category of "better" at 12 weeks
Gabapentin vs placebo
no estimate extracted1 study · 150 participantsVery low
Withdrawals due to adverse events
Gabapentin vs placebo
no estimate extracted1 study · 150 participantsVery low
Serious adverse events
Gabapentin vs placebo
no estimate extracted1 study · 150 participantsVery low
Deaths
Gabapentin vs placebo
no estimate extracted1 study · 150 participantsVery low