Cochrane · systematic review · CD012088

Efficacy and safety of ablation for people with non‐paroxysmal atrial fibrillation

Nyong, J, Amit, G, Adler, AJ, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 20%Low 3 · 60%Moderate 1 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Ablation compared to antiarrhythmic drug for participants with non‐paroxysmal atrial fibrillation

Population: people with non‐paroxysmal atrial fibrillation
5 questions
OutcomeEffectEvidenceStatus / GRADE
Freedom from atrial arrhythmia
Ablation vs antiarrhythmic drug
RR 1.84 [1.17, 2.88]3 studies · 261 participantsLow
Downgraded: imprecision, inconsistency
Participants needing cardioversion
Ablation vs antiarrhythmic drug
RR 0.62 [0.47, 0.82]3 studies · 261 participantsModerate
Downgraded: imprecision
Cardiac hospitalisation Hospitalisations directly related to ablation or antiarrhythmic drugs
Ablation vs antiarrhythmic drug
RR 0.27 [0.1, 0.72]2 studies · 216 participantsLow
Downgraded: imprecision
Significant bradycardia or need for a pacemaker
Ablation vs antiarrhythmic drug
RR 0.2 [0.02, 1.63]3 studies · 261 participantsLow
Downgraded: imprecision
Periprocedural complications and other safety outcomes
Ablation vs antiarrhythmic drug
RR 0.94 [0.16, 5.68]3 studies · 261 participantsVery low
Downgraded: imprecision, inconsistency