Cochrane · systematic review · CD011866
Psychosocial interventions for stimulant use disorder
Minozzi, S, Saulle, R, Amato, L, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
13
No studies
1
Included studies
NR
No studies 1 · 7.1%Ungraded 0 · 0%Very low 1 · 7.1%Low 4 · 28.6%Moderate 2 · 14.3%High 6 · 42.9%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlySummary of findings table ‐ Any psychosocial intervention compared to no intervention for adults with stimulant use disorder
Population: adults with stimulant use disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dropouts Summary of findings table ‐ Any psychosocial intervention vs no intervention | RR 0.82 [0.74, 0.91] | 29 studies · 4049 participants | High |
Point abstinence, end of treatment Summary of findings table ‐ Any psychosocial intervention vs no intervention | RR 1.15 [0.94, 1.41] | 12 studies · 1293 participants | High |
Point abstinence, longest Summary of findings table ‐ Any psychosocial intervention vs no intervention | RR 1.22 [0.91, 1.62] | 9 studies · 1187 participants | High |
Continuous abstinence, end of treatment Summary of findings table ‐ Any psychosocial intervention vs no intervention | RR 1.89 [1.2, 2.97] | 12 studies · 1770 participants | Moderate Downgraded: publication bias |
Continuous abstinence, longest Summary of findings table ‐ Any psychosocial intervention vs no intervention | RR 1.14 [0.85, 1.54] | 3 studies · 266 participants | Low Downgraded: risk of bias, imprecision |
Frequency of drug intake, end of treatment Summary of findings table ‐ Any psychosocial intervention vs no intervention | no estimate extracted | 9 studies · 1186 participants | High |
Longest period of abstinence Summary of findings table ‐ Any psychosocial intervention vs no intervention | no estimate extracted | 17 studies · 2118 participants | High |
Summary of findings table ‐ Any psychosocial intervention compared to treatment as usual (TAU) for adults with stimulant use disorder
Population: adults with stimulant use disorder
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dropouts Summary of findings table ‐ Any psychosocial intervention vs treatment | RR 0.79 [0.65, 0.97] | 9 studies · 735 participants | High |
Point abstinence, end of treatment Summary of findings table ‐ Any psychosocial intervention vs treatment | RR 1.67 [0.64, 4.31] | 1 study · 128 participants | Low Downgraded: imprecision |
Point abstinence, longest Summary of findings table ‐ Any psychosocial intervention vs treatment | RR 1.31 [0.86, 1.99] | 2 studies · 124 participants | Very low Downgraded: risk of bias |
Continuous abstinence, end of treatment Summary of findings table ‐ Any psychosocial intervention vs treatment | RR 1.18 [0.92, 1.53] | 1 study · 128 participants | Low Downgraded: risk of bias |
Frequency of drug intake, end of treatment Summary of findings table ‐ Any psychosocial intervention vs treatment | no estimate extracted | 4 studies · 479 participants | Moderate Downgraded: inconsistency |
Longest period of abstinence Summary of findings table ‐ Any psychosocial intervention vs treatment | no estimate extracted | 1 study · 110 participants | Low Downgraded: risk of bias, imprecision |
Continuous abstinence, longest Summary of findings table ‐ Any psychosocial intervention vs treatment | no estimate extracted | NR | No studies |
Any psychosocial treatment compared to no intervention for psychostimulant misuse
Population: adults (18 years and older) with a diagnosis of psychostimulant misuse
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dropout Any psychosocial treatment vs no intervention | RR 0.83 [0.76, 0.91] | 24 studies · 3393 participants | Moderate Downgraded: risk of bias, imprecision |
Continuous abstinence end of treatment Any psychosocial treatment vs no intervention | RR 2.14 [1.27, 3.59] | 8 studies · 1241 participants | Low Downgraded: risk of bias, inconsistency |
Continuous abstinence longest Any psychosocial treatment vs no intervention | RR 2.12 [0.77, 5.86] | 4 studies · 224 participants | Low Downgraded: risk of bias, imprecision |
Longest period of abstinence Any psychosocial treatment vs no intervention | SMD 0.48 [0.34, 0.63] | 10 studies · 1354 participants | High |
Any psychosocial treatment compared to TAU for psychostimulant misuse
Population: adults (18 years and older) with a diagnosis of psychostimulant misuse
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dropout N of participants not completing treatment Any psychosocial treatment vs TAU | RR 0.72 [0.59, 0.89] | 6 studies · 516 participants | Moderate Downgraded: risk of bias |
Continuous abstinence end of treatment N of participants with continuous abstinence at the end of treatment Any psychosocial treatment vs TAU | RR 1.15 [0.91, 1.46] | 3 studies · 264 participants | Low Downgraded: imprecision, indirectness |
Continuous abstinence longest Any psychosocial treatment vs TAU | no estimate extracted | 0 studies · 0 participants | Ungraded |
Longest period of abstinence Any psychosocial treatment vs TAU | no estimate extracted | 1 study · 110 participants | Low Downgraded: risk of bias, imprecision |