Cochrane · systematic review · CD011737
Reduction in saturated fat intake for cardiovascular disease
Hooper, L, Martin, N, Jimoh, OF, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 3 · 37.5%Low 2 · 25%Moderate 3 · 37.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 3 versionsEffect of reducing saturated fat compared to usual saturated fat on CVD risk in adults (note: for the full set of GRADE tables see additional tables 24 to 28)
Population: people at any baseline risk of CVD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.96 [0.9, 1.03] | 12 studies · 55858 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Cardiovascular mortality Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.94 [0.78, 1.13] | 11 studies · 53421 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Combined cardiovascular events Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.83 [0.7, 0.98] | 13 studies · 53758 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Myocardial infarctions Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.9 [0.8, 1.01] | 11 studies · 53167 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Non‐fatal MI Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.97 [0.87, 1.07] | 8 studies · 52834 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Stroke Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.92 [0.68, 1.25] | 7 studies · 50952 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
CHD mortality Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.97 [0.82, 1.16] | 9 studies · 53159 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
CHD events Effect of reducing saturated fat vs usual saturated fat on CVD risk | RR 0.83 [0.68, 1.01] | 11 studies · 53199 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |