Cochrane · systematic review · CD011710

Internet‐based cognitive and behavioural therapies for post‐traumatic stress disorder (PTSD) in adults

Simon, N, Robertson, L, Lewis, C, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Common Mental Disorders2 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
21
current version
GRADE rated
13
No studies
8
Included studies
NR
No studies 8 · 38.1%Ungraded 0 · 0%Very low 12 · 57.1%Low 1 · 4.8%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Current version only

Internet‐based cognitive and behavioural therapy (I‐C/BT) compared to face‐to‐face non‐CBT for post‐traumatic stress disorder (PTSD) in adults

Population: adults aged ≥ 16 years with PTSD
CD011710.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Severity of PTSD symptoms (measured using the IES‐R, CAPS‐5, PCL‐CPSS‐I, and PDS; higher score = worse outcome)
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
no estimate extracted1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Dropouts
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
RR 2.49 [0.91, 6.77]1 study · 40 participantsVery low
Downgraded: risk of bias, imprecision
Diagnosis of PTSD after treatment
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
no estimate extractedNRNo studies
Severity of depressive symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
no estimate extractedNRNo studies
Severity of anxiety symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
no estimate extractedNRNo studies
Cost‐effectiveness
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
no estimate extractedNRNo studies
Adverse events
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs face‐to‐face non‐CBT
no estimate extractedNRNo studies

Internet‐based cognitive and behavioural therapy (I‐C/BT) compared to wait list for post‐traumatic stress disorder (PTSD) in adults

Population: adults aged ≥ 16 years with PTSD
CD011710.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Severity of PTSD symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extracted10 studies · 608 participantsVery low
Downgraded: risk of bias, inconsistency
Dropouts
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
RR 1.25 [0.97, 1.6]9 studies · 634 participantsLow
Downgraded: risk of bias
Diagnosis of PTSD after treatment
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
RR 0.53 [0.28, 1]1 study · 62 participantsVery low
Downgraded: risk of bias, imprecision
Severity of depressive symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extracted7 studies · 473 participantsVery low
Downgraded: risk of bias, inconsistency
Severity of anxiety symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extracted5 studies · 345 participantsVery low
Downgraded: risk of bias, imprecision
Cost‐effectiveness
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extractedNRNo studies
Adverse events
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision

Internet‐based cognitive and behavioural therapy (I‐C/BT) compared to I‐non‐C/BT for post‐traumatic stress disorder (PTSD) in adults

Population: adults aged ≥ 16 years with PTSD
CD011710.PUB3 (current) · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Severity of PTSD symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extracted2 studies · 82 participantsVery low
Downgraded: risk of bias, imprecision
Dropouts
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
RR 2.14 [0.97, 4.73]2 studies · 132 participantsVery low
Downgraded: risk of bias, imprecision
Diagnosis of PTSD after treatment
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extractedNRNo studies
Severity of depressive symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extracted2 studies · 84 participantsVery low
Downgraded: risk of bias, imprecision
Severity of anxiety symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extracted2 studies · 74 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Cost‐effectiveness
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extractedNRNo studies
Adverse events
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision

Internet‐based cognitive and behavioural therapy (I‐C/BT) compared to wait list for post‐traumatic stress disorder (PTSD) in adults

Population: adults with PTSD
CD011710.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Severity of PTSD symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extracted8 studies · 560 participantsVery low
Downgraded: risk of bias
Dropouts
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
RR 1.39 [1.03, 1.88]8 studies · 585 participantsLow
Downgraded: risk of bias
Diagnosis of PTSD after treatment
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
RR 0.53 [0.28, 1]1 study · 62 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Severity of depressive symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extracted5 studies · 425 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Severity of anxiety symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extracted4 studies · 305 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Cost‐effectiveness
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extractedNRNo studies
Adverse events
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs wait list
no estimate extractedNRNo studies

Internet‐based cognitive and behavioural therapy (I‐C/BT) compared to I‐non‐C/BT for post‐traumatic stress disorder (PTSD) in adults

Population: adults with PTSD
CD011710.PUB2 · 7 questions
OutcomeEffectEvidenceStatus / GRADE
Severity of PTSD symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extracted2 studies · 82 participantsVery low
Downgraded: risk of bias, imprecision
Dropouts
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
RR 2.14 [0.97, 4.73]2 studies · 132 participantsVery low
Downgraded: risk of bias, imprecision
Diagnosis of PTSD after treatment
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extractedNRNo studies
Severity of depressive symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extracted2 studies · 84 participantsVery low
Downgraded: risk of bias, imprecision
Severity of anxiety symptoms (
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extracted2 studies · 74 participantsVery low
Downgraded: risk of bias, imprecision
Cost‐effectiveness
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extractedNRNo studies
Adverse events
Internet‐based cognitive and behavioural therapy (I‐C/BT) vs I‐non‐C/BT
no estimate extractedNRNo studies