Cochrane · systematic review · CD011686

Triage tools for detecting cervical spine injury in paediatric trauma patients

Tavender, E, Eapen, N, Wang, J, et al. · Cochrane Database of Systematic Reviews · 2024 · Cochrane Library

Back and NeckAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 4 · 40%Low 2 · 20%Moderate 4 · 40%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Direct comparisons of clinical decision rules (CDRs) or sets of clinical criteria

Population: children (aged 0 to < 18 years) who underwent blunt trauma evaluation in the emergency department Index test: CDRs or sets of clinical criteria that compared the diagnostic accuracy of the test for cervical spine injury with the reference standard Comparator: studies comparing ≥ 2 CDRs (directly) Reference standard: X‐ray, CT, MRI or clinical clearance/follow‐up in low‐risk children Study types: diagnostic studies with cross‐sectional or cohort designs (retrospective or prospective) and randomised controlled trials
3 questions
OutcomeEffectEvidenceStatus / GRADE
Phillips 2021
no estimate extracted973 participantsModerate
Downgraded: risk of bias
Leonard 2019
no estimate extracted4091 participantsModerate
Downgraded: risk of bias
Davies 2016
no estimate extracted270 participantsVery low
Downgraded: risk of bias, indirectness

Indirect comparisons of clinical decision rules (CDRs) or sets of clinical criteria

Population: children (aged 0 to < 18 years) who underwent blunt trauma evaluation in the emergency department Index test: CDRs that compared the diagnostic accuracy of the test for cervical spine injury with the reference standard Comparator: studies evaluating 1 single CDR or ≥ 2 CDRs (indirectly) Reference standard: X‐ray, CT, MRI or clinical clearance/follow‐up in low‐risk children Study types: diagnostic studies with cross‐sectional or cohort designs (retrospective or prospective) and randomised controlled trials
7 questions
OutcomeEffectEvidenceStatus / GRADE
NEXUS
no estimate extracted2 studies · 4038 participantsLow
Downgraded: risk of bias, imprecision, inconsistency
Canadian C‐Spine Rule
no estimate extracted1 study · 973 participantsModerate
Downgraded: risk of bias
PECARN retrospective
no estimate extracted2 studies · 5064 participantsModerate
Downgraded: risk of bias
Leonard de novo
no estimate extracted1 study · 4091 participantsLow
Downgraded: risk of bias, indirectness
PEDSPINE criteria
no estimate extracted1 study · 12537 participantsVery low
Downgraded: risk of bias, indirectness
NICE CG56
no estimate extracted1 study · 270 participantsVery low
Downgraded: risk of bias, indirectness
NICE CG176
no estimate extracted1 study · 270 participantsVery low
Downgraded: risk of bias, indirectness