Cochrane · systematic review · CD011168
Implantable defibrillators versus medical therapy for cardiac channelopathies
McNamara, DA, Goldberger, JJ, Berendsen, MA, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
HeartAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Implantable cardioverter defibrillators compared to β‐blocker therapy for prevention of sudden cardiac death in people with cardiac channelopathies
Population: people with cardiac channelopathies
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
All‐cause mortality Implantable cardioverter defibrillators vs β‐blocker therapy | RR 0.11 [0.01, 0.83] | 2 studies · 86 participants | Low Downgraded: risk of bias |
Fatal and non‐fatal cardiovascular events Implantable cardioverter defibrillators vs β‐blocker therapy | RR 1.49 [0.66, 3.34] | 2 studies · 86 participants | Low Downgraded: risk of bias |
Adverse events Implantable cardioverter defibrillators vs β‐blocker therapy | RR 2.44 [0.92, 6.44] | 2 studies · 86 participants | Low Downgraded: risk of bias |
Non‐fatal cardiovascular events Implantable cardioverter defibrillators vs β‐blocker therapy | RR 11.44 [1.57, 83.36] | 2 studies · 86 participants | Low Downgraded: risk of bias |
Inappropriate ICD firing Implantable cardioverter defibrillators vs β‐blocker therapy | RR 10.17 [1.32, 78.54] | 2 studies · 86 participants | Low Downgraded: risk of bias |